<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-00849650</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-15T21:03:38+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="fr">Allogeneic haematopoietic stem cell transplantation for myelofibrosis: a report of the Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC).</title>
            <author role="aut">
              <persName>
                <forename type="first">Marie</forename>
                <surname>Robin</surname>
              </persName>
              <idno type="halauthorid">474944-0</idno>
              <affiliation ref="#struct-210517"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Reza</forename>
                <surname>Tabrizi</surname>
              </persName>
              <idno type="halauthorid">364823-0</idno>
              <affiliation ref="#struct-82929"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mohamad</forename>
                <surname>Mohty</surname>
              </persName>
              <email type="md5">325c80de6a308b3a6b83bfd05daad981</email>
              <email type="domain">univ-nantes.fr</email>
              <idno type="idhal" notation="numeric">761875</idno>
              <idno type="halauthorid" notation="string">461502-761875</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-7264-808X</idno>
              <idno type="IDREF">https://www.idref.fr/076744094</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-8536-7781</idno>
              <affiliation ref="#struct-218557"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Sabine</forename>
                <surname>Furst</surname>
              </persName>
              <idno type="halauthorid">725999-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mauricette</forename>
                <surname>Michallet</surname>
              </persName>
              <email type="md5">88ad26ab316972d45e6faae103a2badf</email>
              <email type="domain">chu-lyon.fr</email>
              <idno type="idhal" notation="numeric">1401480</idno>
              <idno type="halauthorid" notation="string">228282-1401480</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-7338-1081</idno>
              <affiliation ref="#struct-25156"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jacques-Olivier</forename>
                <surname>Bay</surname>
              </persName>
              <idno type="halauthorid">186219-0</idno>
              <affiliation ref="#struct-545934"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Yves</forename>
                <surname>Cahn</surname>
              </persName>
              <idno type="halauthorid">204421-0</idno>
              <affiliation ref="#struct-401276"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Eric</forename>
                <surname>de Coninck</surname>
              </persName>
              <idno type="halauthorid">726000-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Nathalie</forename>
                <surname>Dhedin</surname>
              </persName>
              <idno type="halauthorid">709436-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marc</forename>
                <surname>Bernard</surname>
              </persName>
              <idno type="halauthorid">175152-0</idno>
              <affiliation ref="#struct-17835"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Bernard</forename>
                <surname>Rio</surname>
              </persName>
              <idno type="halauthorid">365952-0</idno>
              <affiliation ref="#struct-83294"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Agnès</forename>
                <surname>Buzyn</surname>
              </persName>
              <idno type="halauthorid">161983-0</idno>
              <affiliation ref="#struct-1249"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Anne</forename>
                <surname>Huynh</surname>
              </persName>
              <idno type="halauthorid">308555-0</idno>
              <affiliation ref="#struct-518500"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Karin</forename>
                <surname>Bilger</surname>
              </persName>
              <idno type="halauthorid">709435-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pierre</forename>
                <surname>Bordigoni</surname>
              </persName>
              <idno type="halauthorid">222826-0</idno>
              <affiliation ref="#struct-116528"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Nathalie</forename>
                <surname>Contentin</surname>
              </persName>
              <idno type="halauthorid">440606-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Raphaël</forename>
                <surname>Porcher</surname>
              </persName>
              <email type="md5">e90a771082ea7e45abc6e0a2e55f4102</email>
              <email type="domain">paris7.jussieu.fr</email>
              <idno type="idhal" notation="numeric">756384</idno>
              <idno type="halauthorid" notation="string">138219-756384</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-5277-4679</idno>
              <idno type="IDREF">https://www.idref.fr/071086757</idno>
              <affiliation ref="#struct-3075"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Gérard</forename>
                <surname>Socié</surname>
              </persName>
              <email type="md5">0071b1931570f00bd5a954cde5989b59</email>
              <email type="domain">sls.aphp.fr</email>
              <idno type="idhal" notation="numeric">758626</idno>
              <idno type="halauthorid" notation="string">228175-758626</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-2114-7533</idno>
              <idno type="IDREF">https://www.idref.fr/061658243</idno>
              <affiliation ref="#struct-210517"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Noel</forename>
                <surname>Milpied</surname>
              </persName>
              <idno type="halauthorid">285560-0</idno>
              <affiliation ref="#struct-145452"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Marie-Claire</forename>
                <surname>Dagher</surname>
              </persName>
              <email type="md5">16a92a66fdebde7a6e37680303039cc5</email>
              <email type="domain">ibs.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2013-07-31 15:40:53</date>
              <date type="whenModified">2026-04-23 14:50:04</date>
              <date type="whenReleased">2013-07-31 15:40:53</date>
              <date type="whenProduced">2011-02</date>
              <ref type="externalLink" target="https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2141.2010.08417.x"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="140374">
                <persName>
                  <forename>Marie-Claire</forename>
                  <surname>Dagher</surname>
                </persName>
                <email type="md5">16a92a66fdebde7a6e37680303039cc5</email>
                <email type="domain">ibs.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-00849650</idno>
            <idno type="halUri">https://hal.science/hal-00849650</idno>
            <idno type="halBibtex">robin:hal-00849650</idno>
            <idno type="halRefHtml">&lt;i&gt;British Journal of Haematology&lt;/i&gt;, 2011, 152 (3), pp.331-9. &lt;a target="_blank" href="https://dx.doi.org/10.1111/j.1365-2141.2010.08417.x"&gt;&amp;#x27E8;10.1111/j.1365-2141.2010.08417.x&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">British Journal of Haematology, 2011, 152 (3), pp.331-9. &amp;#x27E8;10.1111/j.1365-2141.2010.08417.x&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="UNIV-ST-ETIENNE">Université Jean Monnet - Saint-Etienne</idno>
            <idno type="stamp" n="UNIV-PARIS5" corresp="UNIV-PARIS">Université Paris Descartes (Paris 5)</idno>
            <idno type="stamp" n="UNIV-PARIS7" corresp="UNIV-PARIS">Université Denis Diderot - Paris VII</idno>
            <idno type="stamp" n="UNIV-NANTES">Université de Nantes</idno>
            <idno type="stamp" n="IOGS" corresp="PARISTECH">Institut d'Optique Graduate School</idno>
            <idno type="stamp" n="HCL">Hospices Civils de Lyon</idno>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="IMAG">IMAG</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-GRENOBLE1">Université Joseph Fourier - Grenoble I</idno>
            <idno type="stamp" n="UNIV-ANGERS">Université d'Angers</idno>
            <idno type="stamp" n="INPG">Institut polytechnique de Grenoble</idno>
            <idno type="stamp" n="APHP" corresp="INSERM">AP-HP</idno>
            <idno type="stamp" n="PARISTECH">ParisTech</idno>
            <idno type="stamp" n="HEH" corresp="HCL">Hôpital Edouard Herriot</idno>
            <idno type="stamp" n="TIMC-IMAG">TIMC</idno>
            <idno type="stamp" n="TIMC-IMAG-THEREX" corresp="TIMC-IMAG">TheREx : Thérapeutique Recombinante Expérimentale</idno>
            <idno type="stamp" n="CRCNA">Centre de recherche en cancérologie Nantes-Angers Unité Mixte de Recherche 892 Inserm - 6299 CNRS</idno>
            <idno type="stamp" n="UDL">UDL</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="UP-SANTE">Université Paris Cité - Faculté de Santé</idno>
            <idno type="stamp" n="CRCI2NA">Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes-Angers</idno>
            <idno type="stamp" n="NANTES-UNIVERSITE">Nantes Université</idno>
            <idno type="stamp" n="UNIV-NANTES-AV2022">Université de Nantes</idno>
            <idno type="stamp" n="UFR-MEDECINE-NANTES">UFR de médecine - Nantes Université</idno>
            <idno type="stamp" n="LABORATOIRE-HUBERT-CURIEN" corresp="UNIV-ST-ETIENNE">LAboratoire Hubert Curien</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="fr">Allogeneic haematopoietic stem cell transplantation for myelofibrosis: a report of the Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC).</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Marie</forename>
                    <surname>Robin</surname>
                  </persName>
                  <idno type="halauthorid">474944-0</idno>
                  <affiliation ref="#struct-210517"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Reza</forename>
                    <surname>Tabrizi</surname>
                  </persName>
                  <idno type="halauthorid">364823-0</idno>
                  <affiliation ref="#struct-82929"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mohamad</forename>
                    <surname>Mohty</surname>
                  </persName>
                  <email type="md5">325c80de6a308b3a6b83bfd05daad981</email>
                  <email type="domain">univ-nantes.fr</email>
                  <idno type="idhal" notation="numeric">761875</idno>
                  <idno type="halauthorid" notation="string">461502-761875</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-7264-808X</idno>
                  <idno type="IDREF">https://www.idref.fr/076744094</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-8536-7781</idno>
                  <affiliation ref="#struct-218557"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Sabine</forename>
                    <surname>Furst</surname>
                  </persName>
                  <idno type="halauthorid">725999-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mauricette</forename>
                    <surname>Michallet</surname>
                  </persName>
                  <email type="md5">88ad26ab316972d45e6faae103a2badf</email>
                  <email type="domain">chu-lyon.fr</email>
                  <idno type="idhal" notation="numeric">1401480</idno>
                  <idno type="halauthorid" notation="string">228282-1401480</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-7338-1081</idno>
                  <affiliation ref="#struct-25156"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jacques-Olivier</forename>
                    <surname>Bay</surname>
                  </persName>
                  <idno type="halauthorid">186219-0</idno>
                  <affiliation ref="#struct-545934"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Yves</forename>
                    <surname>Cahn</surname>
                  </persName>
                  <idno type="halauthorid">204421-0</idno>
                  <affiliation ref="#struct-401276"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Eric</forename>
                    <surname>de Coninck</surname>
                  </persName>
                  <idno type="halauthorid">726000-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Nathalie</forename>
                    <surname>Dhedin</surname>
                  </persName>
                  <idno type="halauthorid">709436-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marc</forename>
                    <surname>Bernard</surname>
                  </persName>
                  <idno type="halauthorid">175152-0</idno>
                  <affiliation ref="#struct-17835"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Bernard</forename>
                    <surname>Rio</surname>
                  </persName>
                  <idno type="halauthorid">365952-0</idno>
                  <affiliation ref="#struct-83294"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Agnès</forename>
                    <surname>Buzyn</surname>
                  </persName>
                  <idno type="halauthorid">161983-0</idno>
                  <affiliation ref="#struct-1249"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Anne</forename>
                    <surname>Huynh</surname>
                  </persName>
                  <idno type="halauthorid">308555-0</idno>
                  <affiliation ref="#struct-518500"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Karin</forename>
                    <surname>Bilger</surname>
                  </persName>
                  <idno type="halauthorid">709435-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pierre</forename>
                    <surname>Bordigoni</surname>
                  </persName>
                  <idno type="halauthorid">222826-0</idno>
                  <affiliation ref="#struct-116528"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Nathalie</forename>
                    <surname>Contentin</surname>
                  </persName>
                  <idno type="halauthorid">440606-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Raphaël</forename>
                    <surname>Porcher</surname>
                  </persName>
                  <email type="md5">e90a771082ea7e45abc6e0a2e55f4102</email>
                  <email type="domain">paris7.jussieu.fr</email>
                  <idno type="idhal" notation="numeric">756384</idno>
                  <idno type="halauthorid" notation="string">138219-756384</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-5277-4679</idno>
                  <idno type="IDREF">https://www.idref.fr/071086757</idno>
                  <affiliation ref="#struct-3075"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Gérard</forename>
                    <surname>Socié</surname>
                  </persName>
                  <email type="md5">0071b1931570f00bd5a954cde5989b59</email>
                  <email type="domain">sls.aphp.fr</email>
                  <idno type="idhal" notation="numeric">758626</idno>
                  <idno type="halauthorid" notation="string">228175-758626</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-2114-7533</idno>
                  <idno type="IDREF">https://www.idref.fr/061658243</idno>
                  <affiliation ref="#struct-210517"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Noel</forename>
                    <surname>Milpied</surname>
                  </persName>
                  <idno type="halauthorid">285560-0</idno>
                  <affiliation ref="#struct-145452"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">11322</idno>
                <idno type="issn">0007-1048</idno>
                <idno type="eissn">1365-2141</idno>
                <title level="j">British Journal of Haematology</title>
                <imprint>
                  <publisher>Wiley</publisher>
                  <biblScope unit="volume">152</biblScope>
                  <biblScope unit="issue">3</biblScope>
                  <biblScope unit="pp">331-9</biblScope>
                  <date type="datePub">2011-02</date>
                  <date type="dateEpub">2010-12-07</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1111/j.1365-2141.2010.08417.x</idno>
              <idno type="pubmed">21133885</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <classCode scheme="mesh">Adult</classCode>
              <classCode scheme="mesh">Aged</classCode>
              <classCode scheme="mesh">Middle Aged</classCode>
              <classCode scheme="mesh">Primary Myelofibrosis</classCode>
              <classCode scheme="mesh">Prognosis</classCode>
              <classCode scheme="mesh">Recurrence</classCode>
              <classCode scheme="mesh">Splenectomy</classCode>
              <classCode scheme="mesh">Transplantation Conditioning</classCode>
              <classCode scheme="mesh">Treatment Outcome</classCode>
              <classCode scheme="mesh">Young Adult</classCode>
              <classCode scheme="mesh">Epidemiologic Methods</classCode>
              <classCode scheme="mesh">Female</classCode>
              <classCode scheme="mesh">Graft Survival</classCode>
              <classCode scheme="mesh">Graft vs Host Disease</classCode>
              <classCode scheme="mesh">Hematopoietic Stem Cell Transplantation</classCode>
              <classCode scheme="mesh">Histocompatibility</classCode>
              <classCode scheme="mesh">Humans</classCode>
              <classCode scheme="mesh">Male</classCode>
              <classCode scheme="halDomain" n="sdv.can">Life Sciences [q-bio]/Cancer</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Allogeneic haematopoietic stem-cell transplantation (HSCT) is the only curative treatment for myelofibrosis. We report an analysis of the Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC) registry including patients with myelofibrosis transplanted between 1997 and 2008. Potential risk factors affecting engraftment, non-relapse mortality (NRM), overall survival (OS) and progression-free survival (PFS) were analysed. One hundred and forty-seven patients, aged 20-68 (median 53) years, diagnosed with primary (53%) or secondary myelofibrosis underwent HSCT; 59% of patients were transplanted from a matched sibling donor. The conditioning regimen was myeloablative in 31% of patients. Ninety percent of the patients engrafted. Factors affecting favourably engraftment were splenectomy before HSCT, human leucocyte antigen (HLA) matched sibling donor, peripheral stem cell use as source of stem cells and absence of pre-transplant thrombocytopenia. Four-year OS, PFS and NRM survival were 39% (95%confidence interval [CI]: 31-50), 32% (95%CI: 24-43) and 39% (95%CI 30-48), respectively. Multivariate analysis indicated that HLA-identical sibling donor, chronic phase disease and splenectomy in men had favourable impact on OS.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-210517" status="INCOMING">
          <orgName>Service d'hématologie greffe [Saint-Louis]</orgName>
          <desc>
            <address>
              <addrLine>1, avenue Claude Vellefaux 75475 Paris 10</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
            <relation active="#struct-300301" type="direct"/>
            <relation active="#struct-421654" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-82929" status="INCOMING">
          <orgName>Hôpital Haut-Lévêque</orgName>
          <desc>
            <address>
              <addrLine>Avenue de Magellan, 33604 Pessac</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-92972" type="direct"/>
            <relation active="#struct-300122" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-218557" status="OLD">
          <orgName>Centre de Recherche en Cancérologie Nantes-Angers</orgName>
          <orgName type="acronym">CRCNA</orgName>
          <date type="end">2016-12-31</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-74911" type="direct"/>
            <relation active="#struct-151939" type="direct"/>
            <relation name="U892" active="#struct-303623" type="direct"/>
            <relation name="UMR6299" active="#struct-441569" type="direct"/>
            <relation active="#struct-474972" type="direct"/>
            <relation active="#struct-531638" type="direct"/>
            <relation active="#struct-93263" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-25156" status="VALID">
          <orgName>Service d'hématologie [Hôpital Edouard Herriot - HCL]</orgName>
          <desc>
            <address>
              <addrLine>5, place d'Arsonval - 69437 LYON cedex 03</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300094" type="direct"/>
            <relation active="#struct-300074" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-545934" status="VALID">
          <orgName>Laboratoire OncoGènAuvergne [Centre Jean Perrin - Clermont-Ferrand]</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cjp.fr/patient-et-proche/diagnostic/laboratoire-oncogenauvergne</ref>
          </desc>
          <listRelation>
            <relation active="#struct-30615" type="direct"/>
            <relation active="#struct-502406" type="indirect"/>
          </listRelation>
        </org>
        <org type="researchteam" xml:id="struct-401276" status="INCOMING">
          <orgName>TheREx</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-707" type="direct"/>
            <relation active="#struct-51016" type="indirect"/>
            <relation active="#struct-89889" type="indirect"/>
            <relation active="#struct-301767" type="indirect"/>
            <relation name="UMR5525" active="#struct-441569" type="indirect"/>
            <relation active="#struct-95138" type="direct"/>
            <relation active="#struct-257328" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-17835" status="VALID">
          <idno type="IdRef">164609741</idno>
          <idno type="ISNI">0000 0000 9955 0977</idno>
          <idno type="RNSR">199511960B</idno>
          <idno type="ROR">https://ror.org/0028p8r67</idno>
          <orgName>Laboratoire Hubert Curien</orgName>
          <orgName type="acronym">LabHC</orgName>
          <date type="start">2006-01-01</date>
          <desc>
            <address>
              <addrLine>Bâtiment F 18 Rue du Professeur Benoît Lauras42000 Saint-Etienne</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://laboratoirehubertcurien.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300036" type="direct"/>
            <relation active="#struct-300284" type="direct"/>
            <relation active="#struct-1327915" type="indirect"/>
            <relation name="UMR5516" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-83294" status="INCOMING">
          <orgName>Département d'Hématologie et Oncologie Médicale</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1249" status="OLD">
          <orgName>Institut Cochin</orgName>
          <orgName type="acronym">UMR_S567 / UMR 8104</orgName>
          <date type="start">2002</date>
          <date type="end">2010</date>
          <desc>
            <address>
              <addrLine>Bâtiment MECHAIN 22 rue Méchain 75014 PARIS</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cochin.inserm.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301664" type="direct"/>
            <relation name="U567" active="#struct-303623" type="direct"/>
            <relation name="UMR 8104" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-518500" status="VALID">
          <orgName>Service Hématologie - IUCT-Oncopole [CHU Toulouse]</orgName>
          <desc>
            <address>
              <addrLine>Institut Universitaire du Cancer de Toulouse - Oncopole, 1, avenue Irène Joliot-Curie - 31059 Toulouse cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-toulouse.fr/-hematologie-laboratoire-iuct-oncopole-</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1041042" type="direct"/>
            <relation active="#struct-300075" type="indirect"/>
            <relation active="#struct-1153022" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-116528" status="INCOMING">
          <orgName>Unité de Transplantation Médullaire</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300157" type="direct"/>
            <relation active="#struct-306764" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-3075" status="OLD">
          <orgName>Biostatistique et épidemiologie clinique</orgName>
          <desc>
            <address>
              <addrLine>Hopital Saint-Louis PARIS VII 1, Avenue Claude Vellefaux 75475 PARIS CEDEX 10</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300301" type="direct"/>
            <relation name="U717" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-145452" status="INCOMING">
          <orgName>Haematology</orgName>
          <desc>
            <address>
              <addrLine>BORDEAUX</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300122" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-300068" status="VALID">
          <idno type="ROR">https://ror.org/00pg5jh14</idno>
          <orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName>
          <orgName type="acronym">AP-HP</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300301" status="OLD">
          <idno type="IdRef">027542084</idno>
          <idno type="ISNI">0000000121514068</idno>
          <idno type="ROR">https://ror.org/02n7qrg46</idno>
          <orgName>Université Paris Diderot - Paris 7</orgName>
          <orgName type="acronym">UPD7</orgName>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>5 rue Thomas-Mann - 75205 Paris cedex 13</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-paris-diderot.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-421654" status="VALID">
          <orgName>Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris]</orgName>
          <desc>
            <address>
              <addrLine>200 rue du Faubourg Saint-Denis 75475 Paris (Nord) Cedex 10</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-92972" status="VALID">
          <orgName>Université Sciences et Technologies - Bordeaux 1</orgName>
          <orgName type="acronym">UB</orgName>
          <date type="start">1971-01-01</date>
          <date type="end">2013-12-31</date>
          <desc>
            <address>
              <addrLine>351 cours de la Libération - 33405 Talence.</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.u-bordeaux1.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300122" status="VALID">
          <idno type="IdRef">028228421</idno>
          <idno type="ROR">https://ror.org/01hq89f96</idno>
          <orgName>Centre Hospitalier Universitaire de Bordeaux</orgName>
          <orgName type="acronym">CHU Bordeaux</orgName>
          <desc>
            <address>
              <addrLine>12 rue Dubernat 33400 Talence</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-bordeaux.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-74911" status="VALID">
          <idno type="IdRef">026402920</idno>
          <idno type="ISNI">0000000122483363</idno>
          <idno type="ROR">https://ror.org/04yrqp957</idno>
          <orgName>Université d'Angers</orgName>
          <orgName type="acronym">UA</orgName>
          <date type="start">1971-10-25</date>
          <desc>
            <address>
              <addrLine>Université d'Angers - 40 Rue de Rennes, BP 73532 - 49035 Angers CEDEX 01</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-angers.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-151939" status="VALID">
          <idno type="ISNI">0000 0004 0472 0283</idno>
          <idno type="ROR">https://ror.org/0250ngj72</idno>
          <orgName>Centre Hospitalier Universitaire d'Angers</orgName>
          <orgName type="acronym">CHU Angers</orgName>
          <desc>
            <address>
              <addrLine>4 rue Larrey - 49933 Angers cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-angers.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-474972" status="VALID">
          <idno type="IdRef">034926445</idno>
          <idno type="ROR">https://ror.org/05c1qsg97</idno>
          <idno type="Wikidata">Q2945767</idno>
          <orgName>Centre Hospitalier Universitaire de Nantes = Nantes University Hospital</orgName>
          <orgName type="acronym">CHU Nantes</orgName>
          <desc>
            <address>
              <addrLine>1 Place Alexis-Ricordeau, 44000 Nantes</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-nantes.fr</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-531638" status="OLD">
          <idno type="IdRef">076954927</idno>
          <orgName>Université de Nantes - UFR de Médecine et des Techniques Médicales</orgName>
          <orgName type="acronym">UFR MEDECINE</orgName>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>1 rue Gaston Veil BP 53508 44035 NANTES Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.medecine.univ-nantes.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-93263" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-93263" status="OLD">
          <idno type="IdRef">026403447</idno>
          <idno type="ROR">https://ror.org/03gnr7b55</idno>
          <orgName>Université de Nantes</orgName>
          <orgName type="acronym">UN</orgName>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>1, quai de Tourville - BP 13522 - 44035 Nantes cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-nantes.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300094" status="VALID">
          <idno type="ROR">https://ror.org/02qt1p572</idno>
          <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName>
          <desc>
            <address>
              <addrLine>5 Place d'Arsonval69003 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300074" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-300074" status="VALID">
          <idno type="IdRef">026534657</idno>
          <idno type="ROR">https://ror.org/01502ca60</idno>
          <orgName>Hospices Civils de Lyon</orgName>
          <orgName type="acronym">HCL</orgName>
          <desc>
            <address>
              <addrLine>3 Quai des Célestins69002 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-30615" status="VALID">
          <idno type="ISNI">0000 0004 1795 1689</idno>
          <idno type="ROR">https://ror.org/02pwnhd33</idno>
          <orgName>Centre Jean Perrin [Clermont-Ferrand]</orgName>
          <orgName type="acronym">UNICANCER/CJP</orgName>
          <desc>
            <address>
              <addrLine>58 rue Montalembert, 63011 Clermont-Ferrand</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cjp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-502406" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-502406" status="VALID">
          <orgName>UNICANCER</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75654 Paris Cedex 13</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.unicancer.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-707" status="OLD">
          <idno type="IdRef">14728936X</idno>
          <idno type="ISNI">0000 0004 4687 1979</idno>
          <idno type="RNSR">199511969L</idno>
          <idno type="ROR">https://ror.org/03985kf35</idno>
          <orgName>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525</orgName>
          <orgName type="acronym">TIMC-IMAG</orgName>
          <date type="start">1993-01-01</date>
          <date type="end">2015-12-31</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www-timc.imag.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-51016" type="direct"/>
            <relation active="#struct-89889" type="direct"/>
            <relation active="#struct-301767" type="direct"/>
            <relation name="UMR5525" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-51016" status="OLD">
          <idno type="IdRef">026404796</idno>
          <idno type="ROR">https://ror.org/02aj0kh94</idno>
          <orgName>Université Joseph Fourier - Grenoble 1</orgName>
          <orgName type="acronym">UJF</orgName>
          <date type="end">2015-12-31</date>
          <desc>
            <address>
              <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ujf-grenoble.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-89889" status="OLD">
          <idno type="IdRef">026388804</idno>
          <idno type="ROR">https://ror.org/05sbt2524</idno>
          <orgName>Institut polytechnique de Grenoble - Grenoble Institute of Technology</orgName>
          <orgName type="acronym">Grenoble INP</orgName>
          <date type="start">2007-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>46 avenue Félix Viallet 38031 Grenoble Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.grenoble-inp.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301767" status="VALID">
          <idno type="ROR">https://ror.org/01c7wz417</idno>
          <orgName>VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement</orgName>
          <orgName type="acronym">VAS</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Lyon, VetAgro Sup, 69280 Marcy l'Etoile (campus vétérinaire); Université de Clermont, VetAgro Sup, 63370 Lempdes (campus agronomique)</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.vetagro-sup.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-95138" status="INCOMING">
          <orgName>Hematology</orgName>
          <desc>
            <address>
              <addrLine>Grenoble</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-51016" type="direct"/>
            <relation active="#struct-257328" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-257328" status="VALID">
          <idno type="IdRef">034137076</idno>
          <idno type="ROR">https://ror.org/041rhpw39</idno>
          <orgName>CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble</orgName>
          <orgName type="acronym">CHUGA</orgName>
          <desc>
            <address>
              <addrLine>CS 1021738043 Grenoble cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-grenoble.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300036" status="VALID">
          <idno type="IdRef">110047702</idno>
          <orgName>Institut d'Optique Graduate School</orgName>
          <orgName type="acronym">IOGS</orgName>
          <desc>
            <address>
              <addrLine>2 avenue Augustin Fresnel, 91127 Palaiseau Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.institutoptique.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300284" status="VALID">
          <idno type="IdRef">028209966</idno>
          <idno type="ISNI">0000 0001 2158 1682</idno>
          <idno type="ROR">https://ror.org/04yznqr36</idno>
          <idno type="Wikidata">Q623154</idno>
          <orgName>Université Jean Monnet - Saint-Étienne</orgName>
          <orgName type="acronym">UJM</orgName>
          <date type="start">1969-03-27</date>
          <date type="end">2025-01-01</date>
          <desc>
            <address>
              <addrLine>10, Rue Tréfilerie – CS 8230142023 Saint-Étienne Cedex 2</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-st-etienne.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1327915" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-1327915" status="VALID">
          <idno type="IdRef">285395831</idno>
          <orgName>Université Jean Monnet (EPSCPE)</orgName>
          <orgName type="acronym">UJM EPE</orgName>
          <date type="start">2025-01-01</date>
          <desc>
            <address>
              <addrLine>10 rue Tréfilerie42100 Saint-Etienne</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-st-etienne.fr/fr/index.html</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301664" status="OLD">
          <idno type="IdRef">026404788</idno>
          <idno type="ISNI">0000 0001 2188 0914 </idno>
          <idno type="ROR">https://ror.org/0220k9r37</idno>
          <orgName>Université Paris Descartes - Paris 5</orgName>
          <orgName type="acronym">UPD5</orgName>
          <date type="start">1971-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>12, rue de l'École de Médecine - 75270 Paris cedex 06</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.parisdescartes.fr/</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-1041042" status="VALID">
          <orgName>Pôle Biologie [CHU Toulouse]</orgName>
          <desc>
            <address>
              <addrLine>Toulouse</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300075" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300075" status="VALID">
          <orgName>Centre Hospitalier Universitaire de Toulouse</orgName>
          <orgName type="acronym">CHU Toulouse</orgName>
          <desc>
            <address>
              <addrLine>regroupe les hôpitaux  Purpan, Rangueil, Pierre-Paul Riquet, Larey, Paule de Viguier, Hôtel Dieu Saint-Jacques, La Grave, etc.</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-toulouse.fr</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-1153022" status="VALID">
          <orgName>Pôle IUCT [CHU Toulouse]</orgName>
          <desc>
            <address>
              <addrLine>Toulouse</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300075" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300157" status="VALID">
          <orgName>Centre Hospitalier Régional Universitaire de Nancy</orgName>
          <orgName type="acronym">CHRU Nancy</orgName>
          <desc>
            <address>
              <addrLine>Siège social : 29 avenue du Maréchal de Lattre de Tassigny, CO 60034, 54035 NANCY CEDEXHôpital Central : 29 Avenue du Maréchal de Lattre de Tassigny, 54035 NancyHôpitaux de Brabois / Enfants : Rue du Morvan, 54500 Vandœuvre-lès-NancyMaternité régionale :10 Avenue Dr Heydenreich, 54000 Nancy</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-nancy.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-306764" status="INCOMING">
          <orgName>Hôpital d'enfants</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>