<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-00849549</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-23T16:14:05+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Self-adjuvanting influenza candidate vaccine presenting epitopes for cell-mediated immunity on a proteinaceous multivalent nanoplatform.</title>
            <author role="aut">
              <persName>
                <forename type="first">Inga</forename>
                <surname>Szurgot</surname>
              </persName>
              <idno type="halauthorid">725878-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Ewa</forename>
                <surname>Szolajska</surname>
              </persName>
              <idno type="halauthorid">709499-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">David</forename>
                <surname>Laurin</surname>
              </persName>
              <email type="md5">e138aa9217d2586f1419602ecd9bebf8</email>
              <email type="domain">efs.sante.fr</email>
              <idno type="idhal" notation="string">david-laurin</idno>
              <idno type="idhal" notation="numeric">1200358</idno>
              <idno type="halauthorid" notation="string">464687-1200358</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-9339-8369</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/M-7895-2014</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/M-7895-2014</idno>
              <affiliation ref="#struct-396554"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Benedicte</forename>
                <surname>Lambrecht</surname>
              </persName>
              <idno type="halauthorid">725879-0</idno>
              <affiliation ref="#struct-133980"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Laurence</forename>
                <surname>Chaperot</surname>
              </persName>
              <email type="md5">18ce8cc9442577f29cea4e6abcc65b68</email>
              <email type="domain">efs.sante.fr</email>
              <idno type="idhal" notation="numeric">1312440</idno>
              <idno type="halauthorid" notation="string">228829-1312440</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1479-9410</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=mKLVh9sAAAAJ</idno>
              <idno type="IDREF">https://www.idref.fr/139764496</idno>
              <idno type="VIAF">https://viaf.org/viaf/189776467</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/N-2927-2013</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/N-2927-2013</idno>
              <affiliation ref="#struct-27442"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Guy</forename>
                <surname>Schoehn</surname>
              </persName>
              <email type="md5">14c19aee7a0b5200dbd84a2c2ef7d3d3</email>
              <email type="domain">ibs.fr</email>
              <idno type="idhal" notation="string">guy-schoehn</idno>
              <idno type="idhal" notation="numeric">738876</idno>
              <idno type="halauthorid" notation="string">5827-738876</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1459-3201</idno>
              <idno type="IDREF">https://www.idref.fr/133454703</idno>
              <affiliation ref="#struct-576"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jadwiga</forename>
                <surname>Chroboczek</surname>
              </persName>
              <email type="md5">a4460b2ece158a242b88fdee21b37ecf</email>
              <email type="domain">ibs.fr</email>
              <idno type="idhal" notation="numeric">967154</idno>
              <idno type="halauthorid" notation="string">919544-967154</idno>
              <orgName ref="#struct-576"/>
              <affiliation ref="#struct-396554"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Marie-Claire</forename>
                <surname>Dagher</surname>
              </persName>
              <email type="md5">16a92a66fdebde7a6e37680303039cc5</email>
              <email type="domain">ibs.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2013-07-31 13:08:21</date>
              <date type="whenModified">2026-04-02 15:38:02</date>
              <date type="whenReleased">2013-07-31 13:08:21</date>
              <date type="whenProduced">2013-07-20</date>
              <ref type="externalLink" target="https://api.istex.fr/ark:/67375/6H6-HDLCX4HB-C/fulltext.pdf?sid=hal"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="140374">
                <persName>
                  <forename>Marie-Claire</forename>
                  <surname>Dagher</surname>
                </persName>
                <email type="md5">16a92a66fdebde7a6e37680303039cc5</email>
                <email type="domain">ibs.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-00849549</idno>
            <idno type="halUri">https://hal.science/hal-00849549</idno>
            <idno type="halBibtex">szurgot:hal-00849549</idno>
            <idno type="halRefHtml">&lt;i&gt;Vaccine&lt;/i&gt;, 2013, epub ahead of print. &lt;a target="_blank" href="https://dx.doi.org/10.1016/j.vaccine.2013.07.021"&gt;&amp;#x27E8;10.1016/j.vaccine.2013.07.021&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Vaccine, 2013, epub ahead of print. &amp;#x27E8;10.1016/j.vaccine.2013.07.021&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="CEA">CEA - Commissariat à l'énergie atomique</idno>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="IMAG">IMAG</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-GRENOBLE1">Université Joseph Fourier - Grenoble I</idno>
            <idno type="stamp" n="INPG">Institut polytechnique de Grenoble</idno>
            <idno type="stamp" n="U823" corresp="INSERM">Institut Albert Bonniot</idno>
            <idno type="stamp" n="TIMC-IMAG">TIMC</idno>
            <idno type="stamp" n="TIMC-IMAG-THEREX" corresp="TIMC-IMAG">TheREx : Thérapeutique Recombinante Expérimentale</idno>
            <idno type="stamp" n="IBS" corresp="CEA">Institut de Biologie Structurale</idno>
            <idno type="stamp" n="IBS-MEM" corresp="IBS">Groupe Microscopie Electronique et Méthodes / Methods and Electron Microscopy Group (IBS-MEM)</idno>
            <idno type="stamp" n="CEA-DRF" corresp="CEA">Direction de Recherche Fondamentale</idno>
            <idno type="stamp" n="IRIG" corresp="CEA">Institut de Recherche Interdisciplinaire de Grenoble</idno>
            <idno type="stamp" n="CEA-GRE" corresp="CEA">CEA Grenoble</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="TEST3-HALCNRS">TEST3-HALCNRS</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Self-adjuvanting influenza candidate vaccine presenting epitopes for cell-mediated immunity on a proteinaceous multivalent nanoplatform.</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Inga</forename>
                    <surname>Szurgot</surname>
                  </persName>
                  <idno type="halauthorid">725878-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Ewa</forename>
                    <surname>Szolajska</surname>
                  </persName>
                  <idno type="halauthorid">709499-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">David</forename>
                    <surname>Laurin</surname>
                  </persName>
                  <email type="md5">e138aa9217d2586f1419602ecd9bebf8</email>
                  <email type="domain">efs.sante.fr</email>
                  <idno type="idhal" notation="string">david-laurin</idno>
                  <idno type="idhal" notation="numeric">1200358</idno>
                  <idno type="halauthorid" notation="string">464687-1200358</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-9339-8369</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/M-7895-2014</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/M-7895-2014</idno>
                  <affiliation ref="#struct-396554"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Benedicte</forename>
                    <surname>Lambrecht</surname>
                  </persName>
                  <idno type="halauthorid">725879-0</idno>
                  <affiliation ref="#struct-133980"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Laurence</forename>
                    <surname>Chaperot</surname>
                  </persName>
                  <email type="md5">18ce8cc9442577f29cea4e6abcc65b68</email>
                  <email type="domain">efs.sante.fr</email>
                  <idno type="idhal" notation="numeric">1312440</idno>
                  <idno type="halauthorid" notation="string">228829-1312440</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1479-9410</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=mKLVh9sAAAAJ</idno>
                  <idno type="IDREF">https://www.idref.fr/139764496</idno>
                  <idno type="VIAF">https://viaf.org/viaf/189776467</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/N-2927-2013</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/N-2927-2013</idno>
                  <affiliation ref="#struct-27442"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Guy</forename>
                    <surname>Schoehn</surname>
                  </persName>
                  <email type="md5">14c19aee7a0b5200dbd84a2c2ef7d3d3</email>
                  <email type="domain">ibs.fr</email>
                  <idno type="idhal" notation="string">guy-schoehn</idno>
                  <idno type="idhal" notation="numeric">738876</idno>
                  <idno type="halauthorid" notation="string">5827-738876</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1459-3201</idno>
                  <idno type="IDREF">https://www.idref.fr/133454703</idno>
                  <affiliation ref="#struct-576"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jadwiga</forename>
                    <surname>Chroboczek</surname>
                  </persName>
                  <email type="md5">a4460b2ece158a242b88fdee21b37ecf</email>
                  <email type="domain">ibs.fr</email>
                  <idno type="idhal" notation="numeric">967154</idno>
                  <idno type="halauthorid" notation="string">919544-967154</idno>
                  <orgName ref="#struct-576"/>
                  <affiliation ref="#struct-396554"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">19820</idno>
                <idno type="issn">0264-410X</idno>
                <idno type="eissn">1873-2518</idno>
                <title level="j">Vaccine</title>
                <imprint>
                  <publisher>Elsevier</publisher>
                  <biblScope unit="pp">epub ahead of print</biblScope>
                  <date type="datePub">2013-07-20</date>
                  <date type="dateEpub">2013-07-20</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.vaccine.2013.07.021</idno>
              <idno type="pubmed">23880363</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <classCode scheme="halDomain" n="sdv.imm.ii">Life Sciences [q-bio]/Immunology/Innate immunity</classCode>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>: We exploit the features of a virus-like particle, adenoviral dodecahedron (Ad Dd), for engineering a multivalent vaccination platform carrying influenza epitopes for cell-mediated immunity. The delivery platform, Ad Dd, is a proteinaceous, polyvalent, and biodegradable nanoparticle endowed with remarkable endocytosis activity that can be engineered to carry 60 copies of a peptide. Influenza M1 is the most abundant influenza internal protein with the conserved primary structure. Two different M1 immunodominant epitopes were separately inserted in Dd external positions without destroying the particles' dodecahedric structure. Both kinds of DdFluM1 obtained through expression in baculovirus system were properly presented by human dendritic cells triggering efficient activation of antigen-specific T cells responses. Importantly, the candidate vaccine was able to induce cellular immunity in vivo in chickens. These results warrant further investigation of Dd as a platform for candidate vaccine, able to stimulate cellular immune responses.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="researchteam" xml:id="struct-396554" status="OLD">
          <orgName>Thérapeutique Recombinante Expérimentale</orgName>
          <orgName type="acronym">TIMC-IMAG-TheREx</orgName>
          <date type="end">2015-12-31</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 37006 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www-timc.imag.fr/THEREX</ref>
          </desc>
          <listRelation>
            <relation active="#struct-707" type="direct"/>
            <relation active="#struct-51016" type="indirect"/>
            <relation active="#struct-89889" type="indirect"/>
            <relation active="#struct-301767" type="indirect"/>
            <relation name="UMR5525" active="#struct-441569" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-133980" status="INCOMING">
          <orgName>VAR</orgName>
          <desc>
            <address>
              <addrLine>Ukkel</addrLine>
              <country key="BE"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-332452" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-27442" status="VALID">
          <orgName>Institut d'oncologie/développement Albert Bonniot de Grenoble</orgName>
          <orgName type="acronym">INSERM U823</orgName>
          <desc>
            <address>
              <addrLine>Institut Albert Bonniot, BP170, 38042 Grenoble Cedex 9</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-51016" type="direct"/>
            <relation active="#struct-199980" type="direct"/>
            <relation active="#struct-257328" type="direct"/>
            <relation name="U823" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="department" xml:id="struct-576" status="OLD">
          <idno type="IdRef">06912633X</idno>
          <idno type="ISNI">0000 0004 0641 5776</idno>
          <idno type="RNSR">199911764W</idno>
          <idno type="ROR">https://ror.org/04szabx38</idno>
          <orgName>Institut de biologie structurale</orgName>
          <orgName type="acronym">IBS - UMR 5075</orgName>
          <date type="start">1992-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>Institut de Biologie Structurale, 71 avenue des martyrs, CS 10090, 38044 Grenoble Cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ibs.fr/</ref>
          </desc>
          <listRelation>
            <relation name="UMR5075 / UPR9015" active="#struct-441569" type="direct"/>
            <relation active="#struct-445543" type="direct"/>
            <relation name="DRF/IRIG/DBSC" active="#struct-555292" type="direct"/>
            <relation name="DRF/IRIG" active="#struct-465913" type="indirect"/>
            <relation active="#struct-300016" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-707" status="OLD">
          <idno type="IdRef">14728936X</idno>
          <idno type="ISNI">0000 0004 4687 1979</idno>
          <idno type="RNSR">199511969L</idno>
          <idno type="ROR">https://ror.org/03985kf35</idno>
          <orgName>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525</orgName>
          <orgName type="acronym">TIMC-IMAG</orgName>
          <date type="start">1993-01-01</date>
          <date type="end">2015-12-31</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www-timc.imag.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-51016" type="direct"/>
            <relation active="#struct-89889" type="direct"/>
            <relation active="#struct-301767" type="direct"/>
            <relation name="UMR5525" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-51016" status="OLD">
          <idno type="IdRef">026404796</idno>
          <idno type="ROR">https://ror.org/02aj0kh94</idno>
          <orgName>Université Joseph Fourier - Grenoble 1</orgName>
          <orgName type="acronym">UJF</orgName>
          <date type="end">2015-12-31</date>
          <desc>
            <address>
              <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ujf-grenoble.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-89889" status="OLD">
          <idno type="IdRef">026388804</idno>
          <idno type="ROR">https://ror.org/05sbt2524</idno>
          <orgName>Institut polytechnique de Grenoble - Grenoble Institute of Technology</orgName>
          <orgName type="acronym">Grenoble INP</orgName>
          <date type="start">2007-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>46 avenue Félix Viallet 38031 Grenoble Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.grenoble-inp.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301767" status="VALID">
          <idno type="ROR">https://ror.org/01c7wz417</idno>
          <orgName>VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement</orgName>
          <orgName type="acronym">VAS</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Lyon, VetAgro Sup, 69280 Marcy l'Etoile (campus vétérinaire); Université de Clermont, VetAgro Sup, 63370 Lempdes (campus agronomique)</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.vetagro-sup.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-332452" status="INCOMING">
          <orgName>VAR</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-199980" status="VALID">
          <orgName>Établissement Français du Sang [La Plaine Saint-Denis]</orgName>
          <orgName type="acronym">EFS</orgName>
          <date type="start">2000-01-01</date>
          <desc>
            <address>
              <addrLine>20 Avenue du Stade de France 93218 La Plaine Saint Denis</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.dondusang.net</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-257328" status="VALID">
          <idno type="IdRef">034137076</idno>
          <idno type="ROR">https://ror.org/041rhpw39</idno>
          <orgName>CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble</orgName>
          <orgName type="acronym">CHUGA</orgName>
          <desc>
            <address>
              <addrLine>CS 1021738043 Grenoble cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-grenoble.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-445543" status="OLD">
          <idno type="IdRef">188399275</idno>
          <idno type="ROR">https://ror.org/02rx3b187</idno>
          <orgName>Université Grenoble Alpes [2016-2019]</orgName>
          <orgName type="acronym">UGA [2016-2019]</orgName>
          <date type="start">2016-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>38058 Grenoble cedex</addrLine>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-555292" status="VALID">
          <idno type="IdRef">240648846</idno>
          <idno type="RNSR">201923169F</idno>
          <idno type="ROR">https://ror.org/00byxdz40</idno>
          <idno type="Wikidata">Q108737333</idno>
          <orgName>Institut de Recherche Interdisciplinaire de Grenoble</orgName>
          <orgName type="acronym">IRIG</orgName>
          <date type="start">2019-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://hal-cea.archives-ouvertes.fr/IRIG/</ref>
          </desc>
          <listRelation>
            <relation name="DRF/IRIG" active="#struct-465913" type="direct"/>
            <relation active="#struct-300016" type="indirect"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-465913" status="VALID">
          <idno type="IdRef">251118436</idno>
          <idno type="RNSR">201622496M</idno>
          <idno type="ROR">https://ror.org/01yvj5k91</idno>
          <idno type="Wikidata">Q52604525</idno>
          <orgName>Direction de Recherche Fondamentale (CEA)</orgName>
          <orgName type="acronym">DRF (CEA)</orgName>
          <date type="start">2016-01-01</date>
          <desc>
            <address>
              <addrLine>Direction de Recherche FondamentaleFundamental Research DivisionCEA Saclay91191 Gif-sur-Yvette</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://ceasciences.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300016" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300016" status="VALID">
          <idno type="IdRef">026372061</idno>
          <idno type="ISNI">0000000122998025</idno>
          <idno type="ROR">https://ror.org/00jjx8s55</idno>
          <idno type="Wikidata">Q868550</idno>
          <orgName>Commissariat à l'énergie atomique et aux énergies alternatives</orgName>
          <orgName type="acronym">CEA</orgName>
          <desc>
            <address>
              <addrLine>Centre de SaclayCentre de GrenobleCentre de Cadaracheetc</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cea.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>