Improvement in protein absorption with a small-peptide-based diet in patients with high jejunostomy. - Archive ouverte HAL
Article Dans Une Revue Nutrition Année : 1993

Improvement in protein absorption with a small-peptide-based diet in patients with high jejunostomy.

D. Evard
  • Fonction : Auteur
J. P. Gendre
  • Fonction : Auteur
Y. Le Quintrec
  • Fonction : Auteur

Résumé

We compared urinary and fecal excretions of fluid, electrolytes, and nutrients in six patients with a high jejunostomy during three randomized consecutive 3-day periods of total enteral nutrition with three diets differing only by the degree of hydrolysis of the protein moiety: whole proteins, their hydrolysate (63% nitrogen as small peptides with < 1000 M), and the two mixed together. Daily nitrogen absorption was significantly enhanced with the small-peptide and mixed diets (14.3 +/- 3.4 and 13.1 +/- 2 g, respectively) compared with the whole protein diet (10.9 +/- 2.4 g, p = 0.012). Concomitantly, blood urea nitrogen and urinary urea excretion increased with the small-peptide diet. Apparent absorption of fat and calories, fecal weight, and urinary and fecal excretions of sodium, potassium, calcium, and magnesium remained unchanged. We conclude that a small-peptide-based diet may be beneficial in patients with short-bowel syndrome.

Domaines

Chimie organique
Fichier non déposé

Dates et versions

hal-00815221 , version 1 (18-04-2013)

Identifiants

  • HAL Id : hal-00815221 , version 1
  • PUBMED : 1486247

Citer

J. Cosnes, D. Evard, L. Beaugerie, J. P. Gendre, Y. Le Quintrec. Improvement in protein absorption with a small-peptide-based diet in patients with high jejunostomy.. Nutrition, 1993, 8 ((6)), pp.406-11. ⟨hal-00815221⟩
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