Palladium-Catalyzed Cross-couplings of Lithium Arylzincates with Aromatic Halides. Synthesis of Analogues of Isomeridianin G and Evaluation as GSK- 3 Inhibitors - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Synthesis: Journal of Synthetic Organic Chemistry Année : 2009

Palladium-Catalyzed Cross-couplings of Lithium Arylzincates with Aromatic Halides. Synthesis of Analogues of Isomeridianin G and Evaluation as GSK- 3 Inhibitors

Résumé

Several analogues of Isomeridianin G have been synthesized using as a key step palladium-catalyzed crosscoupling reactions of lithium triorganozincates. The latter have been prepared by deprotonative lithiation followed by transmetalation using ZnCl2*TMEDA (1/3 equiv).

Domaines

Chimie organique
Fichier principal
Vignette du fichier
Palladium-Catalyzed_Cross-couplings_of_Lithium_Arylzincates_with_Aromatic.pdf (953.6 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-00785036 , version 1 (05-02-2013)

Identifiants

Citer

Anne Seggio, Ghislaine Priem, Floris Chevallier, Florence Mongin. Palladium-Catalyzed Cross-couplings of Lithium Arylzincates with Aromatic Halides. Synthesis of Analogues of Isomeridianin G and Evaluation as GSK- 3 Inhibitors. Synthesis: Journal of Synthetic Organic Chemistry, 2009, 21, pp.3617-3632. ⟨10.1055/s-0029-1217003⟩. ⟨hal-00785036⟩
122 Consultations
469 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More