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Article Dans Une Revue Polymer international Année : 2012

Hydrodynamic Behavior of Dendrigraft Polylysines in Water and Dimethylformamide

Résumé

The four first generations of dendrigraft poly-L-lysine have been studied in dimethylformamide (aprotic solvent) and in 0.2 M NaCl aqueous solutions by isothermal translation diffusion, 1H NMR and viscometry methods. The relationships between diffusion coefficient, intrinsic viscosity and molar mass have been determined for dendrigraft poly-L-lysines, and the scaling index values have been compared to classical trifunctional dendrimers. Dendrimers and dendrigraft poly-L-lysines exhibited similitudes in their hydrodynamic behaviors. Nevertheless, dendrigraft poly-L-lysines displayed a specific behavior in solution. In contrast to dendrimers, a significant change of hydrodynamic dimension of dendrigraft poly-L-lysines according to the nature of the solvent has been observed. In aprotic solvent, the dendrigraft poly-L-lysine dimensions are about two times lower than in aqueous media (i.e., the hydrodynamic volume is contracted by a factor 8 in dimethylformamide), revealing the softness of dendrigraft poly-L-lysine compared to classical trifunctional dendrimers.

Domaines

Chimie organique

Dates et versions

hal-00776801 , version 1 (16-01-2013)

Identifiants

Citer

Natalia Yevlampieva, Anatolii Dobrodumov, Olga Nazarova, Olga Okatava, Hervé Cottet. Hydrodynamic Behavior of Dendrigraft Polylysines in Water and Dimethylformamide. Polymer international, 2012, 4, pp.20-31. ⟨10.3390/polym4010020⟩. ⟨hal-00776801⟩
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