For over 20 years researchers have urged international managers to take culture into account. Focussing on culture raises the problem of using relevant units of analysis. This article advocates that national cultures should be considered even in the global economic context. First, analysis on the national scale makes sense when it is grounded in a political approach to culture. Second, the relevance of the national level is illustrated by the case of Switzerland. If at first sight, Switzerland is a country with multiple internal cultures and borders, a closer analysis shows that the Swiss people share a common political culture based upon attachment to local communities and institutions, to government through consensus and to conflict solving by resorting to arbitration and pragmatism. In the Swiss case, the article shows that management practices are embedded in national political cultures. Validity of the national political culture approach beyond the Swiss case is examined and implications for managers working in cross-cultural environments are discussed.