We set up cosmological perturbation theory and study the cosmological implications of the so-called "generalized Galileon" developed in [6, 7]. This is the most general scalar field theory whose Lagrangian contains derivatives up to second order while keeping second order equations of motion, and contains as sub-cases k-inflation, G-inflation and many other models. We calculate the power spectrum of the primordial curvature perturbation, finding a modification of the usual consistency relation of the tensor-to-scalar ratio in k-inflation or perfect fluid models. Finally we also calculate the bispectrum, which contains no new shapes beyond those of k-inflation.