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Journal Articles Nucleic Acids Research Year : 2012

InterPro in 2011: new developments in the family and domain prediction database

Sarah Hunter
  • Function : Correspondent author
Philip Jones
  • Function : Correspondent author
Alex Mitchell
  • Function : Correspondent author
Edouard de Castro
  • Function : Author
CMU
Nicolas Hulo
  • Function : Author
CMU
Daniel Kahn
Elizabeth Kelly
  • Function : Author
Nicola Mulder
Catherine Rivoire
  • Function : Author
CMU
Christian J. A. Sigrist
  • Function : Author
CMU

Abstract

InterPro (http://www.ebi.ac.uk/interpro/) is a database that integrates diverse information about protein families, domains and functional sites, and makes it freely available to the public via Web-based interfaces and services. Central to the database are diagnostic models, known as signatures, against which protein sequences can be searched to determine their potential function. InterPro has utility in the large-scale analysis of whole genomes and meta-genomes, as well as in characterizing individual protein sequences. Herein we give an overview of new developments in the database and its associated software since 2009, including updates to database content, curation processes and Web and programmatic interfaces.
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Dates and versions

hal-02652188 , version 1 (29-05-2020)

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Sarah Hunter, Philip Jones, Alex Mitchell, Rolf Apweiler, Teresa K. Attwood, et al.. InterPro in 2011: new developments in the family and domain prediction database. Nucleic Acids Research, 2012, 40 (D1), pp.D306-D312. ⟨10.1093/nar/gkr948⟩. ⟨hal-02652188⟩
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