Activation of 1,2-Keto Esters with Takemoto's Catalyst toward Michael Addition to Nitroalkenes
Résumé
When activated with Takemoto's catalyst, 1,2-keto esters constitute versatile nucleophiles in the Michael addition reaction with nitroalkenes affording synthetically valuable, optically active anti-adducts in very good yields and high enantiomeric excesses.