Remarkable stereoselectivity in intramolecular Borono-Mannich reactions: synthesis of conduramines. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Organic Letters Année : 2012

Remarkable stereoselectivity in intramolecular Borono-Mannich reactions: synthesis of conduramines.

Résumé

An unprecedented intramolecular Petasis condensation provides a novel approach to biologically important conduramines. The compounds are produced with an exclusive anti stereoselectivity for the newly created β-amino alcohol motif. The stereochemical outcome of the reaction is opposite to the one usually observed in the intermolecular reaction.

Domaines

Chimie organique
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Dates et versions

hal-00678463 , version 1 (13-03-2012)

Identifiants

Citer

Stéphanie Norsikian, Jean-François Soulé, Alexandre Cannillo, Régis Guillot, Marie-Elise Tran Huu Dau, et al.. Remarkable stereoselectivity in intramolecular Borono-Mannich reactions: synthesis of conduramines.. Organic Letters, 2012, 14 (2), pp.544-7. ⟨10.1021/ol203162s⟩. ⟨hal-00678463⟩
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