Recent trends in the tuning of polymersomes' membrane properties. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue European Physical Journal E: Soft matter and biological physics Année : 2011

Recent trends in the tuning of polymersomes' membrane properties.

Résumé

"Polymersomes" are vesicular structures made from the self-assembly of block copolymers. Such structures present outstanding interest for different applications such as micro- or nano-reactor, drug release or can simply be used as tool for understanding basic biological mechanisms. The use of polymersomes in such applications is strongly related to the way their membrane properties are controlled and tuned either by a precise molecular design of the constituting block or by addition of specific components inside the membrane (formulation approaches). Typical membrane properties of polymersomes obtained from the self-assembly of "coil coil" block copolymer since the end of the nineties will be first briefly reviewed and compared to those of their lipidic analogues, named liposomes. Therefore the different approaches able to modulate their permeability, mechanical properties or ability to release loaded drugs, using macromolecular engineering or formulations, are detailed. To conclude, the most recent advances to modulate the polymersomes' properties and systems that appear very promising especially for biomedical application or for the development of complex and bio-mimetic structures are presented.
Fichier principal
Vignette du fichier
Le Meins EPJE2011 34 14.pdf (812.92 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-00677762 , version 1 (03-11-2018)

Identifiants

Citer

Jean-François Le Meins, Olivier Sandre, Sébastien Lecommandoux. Recent trends in the tuning of polymersomes' membrane properties.. European Physical Journal E: Soft matter and biological physics, 2011, 34 (2), pp.34. ⟨10.1140/epje/i2011-11014-y⟩. ⟨hal-00677762⟩

Collections

CNRS INC-CNRS LCPO
62 Consultations
606 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More