This article is devoted to the dynamics of flexible multi-body systems and to their links with a fundamental set of equations discovered by H. Poincaré one hundred years ago [1]. These equations, called "Poincaré-Chetayev equations", are today known to be the foundation of the Lagrangian reduction theory. Starting with the extension of these equations to a Cosserat medium, we show that the two basic sets of equations used in flexible multi-body dynamics. The generalized Newton-Euler model of flexible multi-body systems in the floating frame approach and the partial differential equations of the nonlinear geometrically exact theory in the Galilean approach, are Poincaré-Chetayev equations.