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Article Dans Une Revue Biomedical optics express Année : 2011

Cramer-Rao analysis of steady-state and time-domain fluorescence diffuse optical imaging

Matthieu Boffety
Marc Allain
Anne Sentenac
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M. Massonneau
  • Fonction : Auteur

Résumé

Using a Cramer-Rao analysis, we study the theoretical performances of a time and spatially resolved fDOT imaging system for jointly estimating the position and the concentration of a point-wide fluorescent volume in a diffusive sample. We show that the fluorescence lifetime is a critical parameter for the precision of the technique. A time resolved fDOT system that does not use spatial information is also considered. In certain cases, a simple steady-state configuration may be as efficient as this time resolved fDOT system.

Dates et versions

hal-00649575 , version 1 (08-12-2011)

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Citer

Matthieu Boffety, Marc Allain, Anne Sentenac, M. Massonneau, Rémi Carminati. Cramer-Rao analysis of steady-state and time-domain fluorescence diffuse optical imaging. Biomedical optics express, 2011, pp.1626-36. ⟨10.1364/BOE.2.001626⟩. ⟨hal-00649575⟩
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