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Article Dans Une Revue Analyst Année : 2007

PCB-based integration of electrochemiluminescence detection for microfluidic systems.

Résumé

This communication presents an instrumental development based on the printed circuit board (PCB) technology to integrate electrochemiluminescence (ECL) analysis in microfluidic systems. PCB gold macro- (10 mm2) and micro- (0.09 mm2) electrodes and two ECL microfluidic devices are designed, fabricated and tested via luminol ECL detection. Potential modulation is performed between 0.7 and 0 V vs. Ag/AgCl for luminol oxidation, thus giving rise to on/off ECL responses in the presence of hydrogen peroxide. Synchronous detection is adopted to allow weak ECL signal recovery at a very low signal-to-noise ratio (SNR). The detection limit obtained with the two ECL microfluidic devices is 50 nM and 100 nM H2O2 for macroelectrodes and microelectrodes, respectively.

Dates et versions

hal-00631232 , version 1 (11-10-2011)

Identifiants

Citer

Patrick Pittet, Guo-Neng Lu, Jean-Marc Galvan, Rosaria Ferrigno, Loïc J Blum, et al.. PCB-based integration of electrochemiluminescence detection for microfluidic systems.. Analyst, 2007, 132 (5), pp.409-11. ⟨10.1039/b701296a⟩. ⟨hal-00631232⟩
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