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            <idno type="halRefHtml">&lt;i&gt;Journal of Antimicrobial Chemotherapy&lt;/i&gt;, 2010, 65 (9), pp.2028-36. &lt;a target="_blank" href="https://dx.doi.org/10.1093/jac/dkq228"&gt;&amp;#x27E8;10.1093/jac/dkq228&amp;#x27E9;&lt;/a&gt;</idno>
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                <title xml:lang="en">Antibiotic use in 530 French hospitals: results from a surveillance network at hospital and ward levels in 2007.</title>
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                    <forename type="first">Anne-Marie</forename>
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                <title level="j">Journal of Antimicrobial Chemotherapy</title>
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                  <date type="datePub">2010-09</date>
                  <date type="dateEpub">2010-06-25</date>
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              <p>OBJECTIVES: Antibiotic use in French hospitals is among the highest in Europe. A study was carried out to describe antibiotic consumption for inpatients at hospital and at ward levels. METHODS: Data were voluntarily collected retrospectively by 530 hospitals accounting for approximately 40 million patient-days (PD) on the following: antibacterials for systemic use [J01 class of the WHO Anatomical Therapeutic Chemical (ATC) classification, defined daily doses (DDD) system, 2007], rifampicin and oral imidazole derivatives, expressed in number of DDD and number of PD in 2007. Consumption was expressed in DDD/1000 PD. RESULTS: Median antibiotic use ranged from 60 DDD/1000 PD in long-term care (LTC) and psychiatric hospitals to 633 DDD/1000 PD in teaching hospitals. Penicillins and beta-lactamase inhibitors combinations were the most frequently used antibiotics, accounting for 26% of total use in cancer hospitals to 40% in LTC/psychiatric hospitals. Glycopeptides and carbapenems were mostly used in cancer and teaching hospitals. Level of consumption and pattern of use differed according to clinical ward from 60 DDD/1000 PD in psychiatric wards up to 1466 DDD/1000 PD in intensive care units (ICUs). In medicine, surgery, ICU and rehabilitation wards, fluoroquinolones accounted for 13%-19% of the total use. CONCLUSIONS: This multicentre survey provided detailed information on antibiotic use in a large sample of hospitals and wards, allowing relevant comparisons and benchmarking. Analysis of consumption at the ward level should help hospitals to target practice audits to improve antibiotic use.</p>
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