Synthesis of 1,6-dihydropyrrolo[2,3-g]indazoles using Larock indole annulations - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Tetrahedron Année : 2011

Synthesis of 1,6-dihydropyrrolo[2,3-g]indazoles using Larock indole annulations

Résumé

The synthesis of 1,6-dihydropyrrolo[2,3-g]indazole derivatives is described. The indolic ring system is constructed via a Larock palladium-catalyzed annulation using terminal and internal alkynes. Additionally, when using internal alkynes for this reaction, we found that a directing effect on regioselectivity was mediated by the ester group of alkyl 3-substituted propiolate derivatives
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Dates et versions

hal-00624642 , version 1 (19-09-2011)

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  • HAL Id : hal-00624642 , version 1

Citer

Laurent Gavara, Fabrice Anizon, Pascale Moreau. Synthesis of 1,6-dihydropyrrolo[2,3-g]indazoles using Larock indole annulations. Tetrahedron, 2011, 67, pp.7330-7335. ⟨hal-00624642⟩
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