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Article Dans Une Revue Computer Methods in Biomechanics and Biomedical Engineering Année : 2011

Traction forces of cancer cells

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Résumé

Cell motility of cancer cells is a fundamental problem, and requires precise correlation between cell adhesive and rheological properties. The migration of cancer cells is studied in two dimensions, as cells are seeded onto functionnalized polyacrylamide gels. They migrate by developping focal adhesion sites and modulate their cytoskeleton dynamics by regulating actin and myosin. This research aims at understanding the forces developped by different cancer cells of moderate to high invasiveness in order to investigate their contractility as well as the adhesion molecules necessary for cell migration.
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Dates et versions

hal-00618952 , version 1 (04-09-2011)

Identifiants

Citer

Valentina Peschetola, Valérie M. Laurent, Alain Duperray, Luigi Preziosi, Davide Ambrosi, et al.. Traction forces of cancer cells. Computer Methods in Biomechanics and Biomedical Engineering, 2011, 14 (S1), pp.159-160. ⟨10.1080/10255842.2011.593954⟩. ⟨hal-00618952⟩
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