A novel performance measurement and assessment frame called Performance Factory (PerFact) applied on a specific example focussing on mass customization in the context of the Factory of the Future is presented in this work. PerFact operates target-oriented towards the mission and vision of the company by connecting the overall mission and vision via related requirements with the Key Performance Indicators (KPIs) and their specific reference values. The performance is measured on manufactured customer-driven products, corresponding production processes and used resources. Furthermore, PerFact is able to monitor and assess the performance of both real production systems and simulated production scenarios. Moreover, the measurement system is balanced; it assesses the performance of the factory considering all perspectives relevant for each specific case.