Genome-wide epigenetic perturbation jump-starts patterns of heritable variation found in nature - Archive ouverte HAL
Article Dans Une Revue Genetics Année : 2011

Genome-wide epigenetic perturbation jump-starts patterns of heritable variation found in nature

M. Colomé-Tatché
  • Fonction : Auteur
R. Wardenaar
  • Fonction : Auteur
Philippe Guerche
F. Hospital
  • Fonction : Auteur
V. Colot
Jansen R. C.
  • Fonction : Auteur
F. Johannes
  • Fonction : Auteur

Résumé

We extensively phenotyped 6000 Arabidopsis plants with experimentally perturbed DNA methylomes as well as a diverse panel of natural accessions in a common garden. We found that alterations in DNA methylation not only caused heritable phenotypic diversity but also produced heritability patterns closely resembling those of the natural accessions. Our findings indicate that epigenetically induced and naturally occurring variation in complex traits share part of their polygenic architecture and may offer complementary adaptation routes in ecological settings.

Dates et versions

hal-00604163 , version 1 (28-06-2011)

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Citer

F. Roux, M. Colomé-Tatché, C. Edelist, R. Wardenaar, Philippe Guerche, et al.. Genome-wide epigenetic perturbation jump-starts patterns of heritable variation found in nature. Genetics, 2011, 189 (4), pp.1015-1017. ⟨10.1534/genetics.111.128744⟩. ⟨hal-00604163⟩
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