DISTAL MUSCLE INVOLVEMENT IN GRANULOMATOUS MYOSITIS CAN MIMIC INCLUSION BODY MYOSITIS
Résumé
We report on four aged patients with chronic myopathy suggestive of sporadic inclusion body myositis. They presented progressive and selective weakness of the quadriceps femoris muscles. Asymmetric and selective atrophy of the forearm muscles was noted in all, with more severe involvement of the flexors than the extensors. Biopsy revealed granulomatous myositis. Histological features of s-IBM were lacking. Evidence for systemic sarcoidosis was found in one patient. Corticosteroids treatment was associated with partial but significant improvement in two patients. Granulomatous myositis may mimick inclusion body myositis and may be steroids responsive.
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