A mechano-biological model to predict the role of implant surfaces in the periprosthetic healing
Résumé
Conditions influencing bone growth in the early post-operative period include the surgical technique, mechanical [Prendergast, 1997] and biochemical factors [Bailón-Plaza, 2001]. Low performances of implant fixation were generally associated with a low mineralization or a strong heterogeneous distribution of bony structure in the new-formed surrounding tissue and the physicochemical properties of the implant surface might pay a significant role. We previously developed a mechanobiological model of healing coupling porous media mechanics to biomathematics [Ambard, 2006]. To go further, we hypothesized that such mathematical model could be completed to investigate the role of implant surface in cell proliferation, migration, and adhesion. The application concerned our stable canine implant [Vestermark, 2004].
Origine | Fichiers produits par l'(les) auteur(s) |
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