Convergence of stochastic gene networks to hybrid piecewise deterministic processes - Archive ouverte HAL
Article Dans Une Revue The Annals of Applied Probability Année : 2012

Convergence of stochastic gene networks to hybrid piecewise deterministic processes

Résumé

We study the asymptotic behavior of multiscale stochastic gene networks using weak limits of Markov jump processes. Depending on the time and concentration scales of the system we distinguish four types of limits: continuous piecewise deterministic processes (PDP) with switching, PDP with jumps in the continuous variables, averaged PDP, and PDP with singular switching. We justify rigorously the convergence for the four types of limits. The convergence results can be used to simplify the stochastic dynamics of gene network models arising in molecular biology.
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Dates et versions

hal-00553482 , version 1 (07-01-2011)

Identifiants

Citer

Alina Crudu, Arnaud Debussche, Aurélie Muller, Ovidiu Radulescu. Convergence of stochastic gene networks to hybrid piecewise deterministic processes. The Annals of Applied Probability, 2012, 22 (5), pp.1822-1859. ⟨10.1214/11-AAP814⟩. ⟨hal-00553482⟩
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