Brain atrophy and lesion load measures over one year relate to clinical status after 6 years in patients with clinically isolated syndromes - Archive ouverte HAL Access content directly
Journal Articles Journal of Neurology, Neurosurgery and Psychiatry Year : 2010

Brain atrophy and lesion load measures over one year relate to clinical status after 6 years in patients with clinically isolated syndromes

Valerie M Anderson
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  • PersonId : 888078
Daniel R Altmann
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  • PersonId : 888079
Josephine K Swanton
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  • PersonId : 888080
Alan J Thompson
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  • PersonId : 888082
David H Miller
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  • PersonId : 888083

Abstract

Conventional MRI lesion measures modestly predict long term disability in some CIS studies. Brain atrophy suggests neuroaxonal loss in MS with the potential to reflect disease progression to a greater extent than lesion measures.

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hal-00552764 , version 1 (06-01-2011)

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Massimiliano Di Filippo, Valerie M Anderson, Daniel R Altmann, Josephine K Swanton, Gordon T Plant, et al.. Brain atrophy and lesion load measures over one year relate to clinical status after 6 years in patients with clinically isolated syndromes. Journal of Neurology, Neurosurgery and Psychiatry, 2010, 81 (2), pp.204. ⟨10.1136/jnnp.2009.171769⟩. ⟨hal-00552764⟩

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