Aromatic Nitrogen Donors for Efficient Copper(I)-NHC CuAAC under reductant-free conditions.
Résumé
Copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) has been successfully conducted under reductant-free conditions. The catalytic system consisted of a combination of a copper(I)-N-heterocyclic carbene complex and aromatic N-donors. The catalyst is stable and can be stored, thus rendering the reaction valuable for routine use