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              <p>We determine the ratio FK/Fpi in QCD with Nf=2+1 flavors of sea quarks, based on a series of lattice calculations with three different lattice spacings, large volumes and a simulated pion mass reaching down to about 190 MeV. We obtain FK/Fpi=1.192 +/- 0.007(stat) +/- 0.006(syst). This result is then used to give an updated value of the CKM matrix element |Vus|. The unitarity relation for the first row of this matrix is found to be well observed.</p>
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