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Article Dans Une Revue Journal of Clinical Microbiology Année : 2010

Comprehensive analysis of a norovirus-associated gastroenteritis outbreak, from the environment to the consumer.

Résumé

Noroviruses have been recognized to be the predominant agents of nonbacterial gastroenteritis outbreaks in humans, and their transmission via contaminated shellfish consumption has been demonstrated. Norovirus laboratory experiments, volunteer challenge studies, and community gastroenteritis outbreak investigations have identified human genetic susceptibility factors related to histo-blood group antigen expression. Following a banquet in Brittany, France, in February 2008, gastroenteritis cases were linked to oyster consumption. This study identified an association of the norovirus illnesses with histo-blood group expression, and oyster contamination with norovirus was confirmed by qualitative and quantitative analyses. The secretor phenotype was associated with illness, especially for the non-A subgroup. The study showed that, in addition to accidental climatic events that may lead to oyster contamination, illegal shellfish collection and trading are also risk factors associated with outbreaks.

Domaines

Virologie

Dates et versions

hal-00474843 , version 1 (21-04-2010)

Identifiants

Citer

Françoise S Le Guyader, Joanna Krol, Katia Ambert-Balay, Nathalie Ruvoen-Clouet, Bénédicte Desaubliaux, et al.. Comprehensive analysis of a norovirus-associated gastroenteritis outbreak, from the environment to the consumer.. Journal of Clinical Microbiology, 2010, 48 (3), pp.915-20. ⟨10.1128/JCM.01664-09⟩. ⟨hal-00474843⟩
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