Propionibacterium endocarditis: a case series from the International Collaboration on Endocarditis Merged Database and Prospective Cohort Study. - Archive ouverte HAL Access content directly
Journal Articles Scandinavian Journal of Infectious Diseases Year : 2007

Propionibacterium endocarditis: a case series from the International Collaboration on Endocarditis Merged Database and Prospective Cohort Study.

Tahaniyat Lalani
  • Function : Author
Anna K Person
  • Function : Author
Susan S Hedayati
  • Function : Author
Laura Moore
  • Function : Author
David R Murdoch
  • Function : Author
Gail Peterson
  • Function : Author
Hasan Shahbaz
  • Function : Author
Jose M Miro
  • Function : Author
Lars Olaison
  • Function : Author
Ulrika Snygg-Martino
  • Function : Author
Fredy Suter
  • Function : Author
Dennis Spelman
  • Function : Author
Susannah Eykyn
  • Function : Author
Jacob Strahilevitz
  • Function : Author
Jan T van Der Meer
  • Function : Author
Dominique Verhagen
  • Function : Author
Khaula Baloch
  • Function : Author
Elias Abrutyn
  • Function : Author
Christopher H Cabell
  • Function : Author
Non Renseigné
  • Function : Author

Abstract

Propionibacterium species are occasionally associated with serious systemic infections such as infective endocarditis. In this study, we examined the clinical features, complications and outcome of 15 patients with Propionibacterium endocarditis using the International Collaboration on Endocarditis Merged Database (ICE-MD) and Prospective Cohort Study (ICE-PCS), and compared the results to 28 cases previously reported in the literature. In the ICE database, 11 of 15 patients were male with a mean age of 52 y. Prosthetic valve endocarditis occurred in 13 of 15 cases and 3 patients had a history of congenital heart disease. Clinical findings included valvular vegetations (9 patients), cardiac abscesses (3 patients), congestive heart failure (2 patients), and central nervous system emboli (2 patients). Most patients were treated with beta-lactam antibiotics alone or in combination for 4 to 6 weeks. 10 of the 15 patients underwent valve replacement surgery and 2 patients died. Similar findings were noted on review of the literature. The results of this paper suggest that risk factors for Propionibacterium endocarditis include male gender, presence of prosthetic valves and congenital heart disease. The clinical course is characterized by complications such as valvular dehiscence, cardiac abscesses and congestive heart failure. Treatment may require a combination of medical and surgical therapy.
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hal-00465333 , version 1 (19-03-2010)

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Tahaniyat Lalani, Anna K Person, Susan S Hedayati, Laura Moore, David R Murdoch, et al.. Propionibacterium endocarditis: a case series from the International Collaboration on Endocarditis Merged Database and Prospective Cohort Study.. Scandinavian Journal of Infectious Diseases, 2007, 39 (10), pp.840-8. ⟨10.1080/00365540701367793⟩. ⟨hal-00465333⟩
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