MiPNO, a new chiral nitrone for enantioselective amino acid synthesis: the cycloaddition approach.
Résumé
The resolution of chiral nitrones via derivatization of hydroxylamines was applied to MiPNO, a new, stable, easily prepared chiral cyclic nitrone. The application of MiPNO in totally regio- and diastereo- selective 1,3-dipolar cycloaddition reactions provides an expeditious enantioselective access to unusual γ-hydroxy α-aminoacids.
Domaines
Chimie organiqueOrigine | Fichiers produits par l'(les) auteur(s) |
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