<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-00453681</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-17T03:43:57+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Accuracy of complete compression ultrasound in ruling out suspected deep venous thrombosis in the ambulatory setting. A prospective cohort study.</title>
            <author role="aut">
              <persName>
                <forename type="first">Marie-Antoinette</forename>
                <surname>Sevestre</surname>
              </persName>
              <email type="md5">994df4ff0771e64eafad0903eb69a087</email>
              <email type="domain">chu-amiens.fr</email>
              <idno type="idhal" notation="numeric">951205</idno>
              <idno type="halauthorid" notation="string">310421-951205</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1779-6936</idno>
              <idno type="IDREF">https://www.idref.fr/070272913</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/FXL-8156-2022</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/FXL-8156-2022</idno>
              <affiliation ref="#struct-388317"/>
            </author>
            <author role="crp">
              <persName>
                <forename type="first">José</forename>
                <surname>Labarère</surname>
              </persName>
              <email type="md5">1a8f7ccb5bd17297b82ff42238a5b967</email>
              <email type="domain">chu-grenoble.fr</email>
              <idno type="idhal" notation="numeric">945776</idno>
              <idno type="halauthorid" notation="string">250976-945776</idno>
              <affiliation ref="#struct-388317"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pierre</forename>
                <surname>Casez</surname>
              </persName>
              <idno type="halauthorid">384000-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Luc</forename>
                <surname>Bressollette</surname>
              </persName>
              <idno type="idhal" notation="numeric">759066</idno>
              <idno type="halauthorid" notation="string">246498-759066</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-8354-469X</idno>
              <affiliation ref="#struct-356603"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mébarka</forename>
                <surname>Taiar</surname>
              </persName>
              <idno type="halauthorid">441066-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Gilles</forename>
                <surname>Pernod</surname>
              </persName>
              <email type="md5">4016f65f8ef2b07d7ce677d2b9f73ccb</email>
              <email type="domain">chu-grenoble.fr</email>
              <idno type="idhal" notation="numeric">1367614</idno>
              <idno type="halauthorid" notation="string">250940-1367614</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-6494-5984</idno>
              <affiliation ref="#struct-388317"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Isabelle</forename>
                <surname>Quéré</surname>
              </persName>
              <email type="md5">fd26d9ed1c41f0d421a4764f4f08469d</email>
              <email type="domain">chu-montpellier.fr</email>
              <idno type="idhal" notation="string">isabelle-quere</idno>
              <idno type="idhal" notation="numeric">1099941</idno>
              <idno type="halauthorid" notation="string">314395-1099941</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1492-9764</idno>
              <idno type="IDREF">https://www.idref.fr/059746734</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Luc</forename>
                <surname>Bosson</surname>
              </persName>
              <email type="md5">012040f0cb3ec469b70d203dbdd88e68</email>
              <email type="domain">imag.fr</email>
              <idno type="idhal" notation="numeric">1349988</idno>
              <idno type="halauthorid" notation="string">145120-1349988</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-0967-6026</idno>
              <idno type="IDREF">https://www.idref.fr/06012282X</idno>
              <idno type="ISNI">http://isni.org/isni/000000035906575X</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/M-6378-2014</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/AAP-5163-2020</idno>
              <idno type="VIAF">https://viaf.org/viaf/9171184718147771676</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/M-6378-2014</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/AAP-5163-2020</idno>
              <affiliation ref="#struct-388317"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Jose</forename>
                <surname>Labarere</surname>
              </persName>
              <email type="md5">1a8f7ccb5bd17297b82ff42238a5b967</email>
              <email type="domain">chu-grenoble.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2010-02-05 14:02:33</date>
              <date type="whenModified">2025-09-27 18:42:06</date>
              <date type="whenReleased">2010-02-05 14:02:33</date>
              <date type="whenProduced">2009-07</date>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="123487">
                <persName>
                  <forename>Jose</forename>
                  <surname>Labarere</surname>
                </persName>
                <email type="md5">1a8f7ccb5bd17297b82ff42238a5b967</email>
                <email type="domain">chu-grenoble.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-00453681</idno>
            <idno type="halUri">https://hal.science/hal-00453681</idno>
            <idno type="halBibtex">sevestre:hal-00453681</idno>
            <idno type="halRefHtml">&lt;i&gt;Thrombosis and Haemostasis&lt;/i&gt;, 2009, 102 (1), pp.166-72. &lt;a target="_blank" href="https://dx.doi.org/10.1160/TH09-01-0048"&gt;&amp;#x27E8;10.1160/TH09-01-0048&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Thrombosis and Haemostasis, 2009, 102 (1), pp.166-72. &amp;#x27E8;10.1160/TH09-01-0048&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="IMAG">IMAG</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-GRENOBLE1">Université Joseph Fourier - Grenoble I</idno>
            <idno type="stamp" n="INPG">Institut polytechnique de Grenoble</idno>
            <idno type="stamp" n="SANTE_PUB_INSERM" corresp="INSERM">Santé Publique à l'Inserm</idno>
            <idno type="stamp" n="TIMC-IMAG">TIMC</idno>
            <idno type="stamp" n="TIMC-IMAG-THEMAS" corresp="TIMC-IMAG">ThEMAS : Techniques pour l'Evaluation et la Modélisation des Actions de Santé</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Accuracy of complete compression ultrasound in ruling out suspected deep venous thrombosis in the ambulatory setting. A prospective cohort study.</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Marie-Antoinette</forename>
                    <surname>Sevestre</surname>
                  </persName>
                  <email type="md5">994df4ff0771e64eafad0903eb69a087</email>
                  <email type="domain">chu-amiens.fr</email>
                  <idno type="idhal" notation="numeric">951205</idno>
                  <idno type="halauthorid" notation="string">310421-951205</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1779-6936</idno>
                  <idno type="IDREF">https://www.idref.fr/070272913</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/FXL-8156-2022</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/FXL-8156-2022</idno>
                  <affiliation ref="#struct-388317"/>
                </author>
                <author role="crp">
                  <persName>
                    <forename type="first">José</forename>
                    <surname>Labarère</surname>
                  </persName>
                  <email type="md5">1a8f7ccb5bd17297b82ff42238a5b967</email>
                  <email type="domain">chu-grenoble.fr</email>
                  <idno type="idhal" notation="numeric">945776</idno>
                  <idno type="halauthorid" notation="string">250976-945776</idno>
                  <affiliation ref="#struct-388317"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pierre</forename>
                    <surname>Casez</surname>
                  </persName>
                  <idno type="halauthorid">384000-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Luc</forename>
                    <surname>Bressollette</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">759066</idno>
                  <idno type="halauthorid" notation="string">246498-759066</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-8354-469X</idno>
                  <affiliation ref="#struct-356603"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mébarka</forename>
                    <surname>Taiar</surname>
                  </persName>
                  <idno type="halauthorid">441066-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Gilles</forename>
                    <surname>Pernod</surname>
                  </persName>
                  <email type="md5">4016f65f8ef2b07d7ce677d2b9f73ccb</email>
                  <email type="domain">chu-grenoble.fr</email>
                  <idno type="idhal" notation="numeric">1367614</idno>
                  <idno type="halauthorid" notation="string">250940-1367614</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-6494-5984</idno>
                  <affiliation ref="#struct-388317"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Isabelle</forename>
                    <surname>Quéré</surname>
                  </persName>
                  <email type="md5">fd26d9ed1c41f0d421a4764f4f08469d</email>
                  <email type="domain">chu-montpellier.fr</email>
                  <idno type="idhal" notation="string">isabelle-quere</idno>
                  <idno type="idhal" notation="numeric">1099941</idno>
                  <idno type="halauthorid" notation="string">314395-1099941</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1492-9764</idno>
                  <idno type="IDREF">https://www.idref.fr/059746734</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Luc</forename>
                    <surname>Bosson</surname>
                  </persName>
                  <email type="md5">012040f0cb3ec469b70d203dbdd88e68</email>
                  <email type="domain">imag.fr</email>
                  <idno type="idhal" notation="numeric">1349988</idno>
                  <idno type="halauthorid" notation="string">145120-1349988</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-0967-6026</idno>
                  <idno type="IDREF">https://www.idref.fr/06012282X</idno>
                  <idno type="ISNI">http://isni.org/isni/000000035906575X</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/M-6378-2014</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/AAP-5163-2020</idno>
                  <idno type="VIAF">https://viaf.org/viaf/9171184718147771676</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/M-6378-2014</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/AAP-5163-2020</idno>
                  <affiliation ref="#struct-388317"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">19627</idno>
                <idno type="issn">0340-6245</idno>
                <title level="j">Thrombosis and Haemostasis</title>
                <imprint>
                  <publisher>Schattauer</publisher>
                  <biblScope unit="volume">102</biblScope>
                  <biblScope unit="issue">1</biblScope>
                  <biblScope unit="pp">166-72</biblScope>
                  <date type="datePub">2009-07</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1160/TH09-01-0048</idno>
              <idno type="pubmed">19572082</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <classCode scheme="mesh">Aged</classCode>
              <classCode scheme="mesh">Ambulatory Care</classCode>
              <classCode scheme="mesh">Prospective Studies</classCode>
              <classCode scheme="mesh">Reproducibility of Results</classCode>
              <classCode scheme="mesh">Ultrasonography</classCode>
              <classCode scheme="mesh">Venous Thrombosis</classCode>
              <classCode scheme="mesh">Anticoagulants</classCode>
              <classCode scheme="mesh">Drug Administration Schedule</classCode>
              <classCode scheme="mesh">Female</classCode>
              <classCode scheme="mesh">Follow-Up Studies</classCode>
              <classCode scheme="mesh">Humans</classCode>
              <classCode scheme="mesh">Leg</classCode>
              <classCode scheme="mesh">Male</classCode>
              <classCode scheme="mesh">Middle Aged</classCode>
              <classCode scheme="halDomain" n="sdv.spee">Life Sciences [q-bio]/Santé publique et épidémiologie</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Evidence on the safety of complete compression ultrasound for ruling out deep venous thrombosis (DVT) is derived from studies conducted in tertiary care centers, although most patients with suspected DVT are managed in the ambulatory office setting. It was the objective of this study to estimate the rate of venous thromboembolism when anticoagulant therapy is withheld from ambulatory patients with normal findings on a single complete compression ultrasound. As part of a prospective cohort study, 3,871 ambulatory patients with clinically suspected DVT were enrolled by 255 board-certified vascular medicine physicians practicing in private offices in France. Compression ultrasound of the entire lower extremities was performed using a standardised examination protocol. Anticoagulant therapy was withheld from patients with negative findings on compression ultrasound, and 1,254 of them were randomly selected for follow-up. The main outcome measure was the three-month incidence of symptomatic venous thromboembolic events confirmed by objective testing. DVT was detected in 1,023 patients (26.4%), including 454 (11.7%) and 569 (14.7%) cases of proximal and isolated distal DVT, respectively. Of the 1,254 patients with negative results sampled for follow-up, six received anticoagulant therapy during follow-up and five were lost to follow-up. Five of 1,243 patients (0.4%, 95% confidence interval [CI], 0.1-0.9) experienced non-fatal symptomatic venous thromboembolic events (pulmonary embolism in two patients and DVT in three patients) and eight of 1,254 patients (0.6%, 95% CI, 0.3-1.2) died during the three-month follow-up. In conclusion, anticoagulant therapy can be safely withheld after negative complete compression ultrasound without further testing in the ambulatory office setting.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="researchteam" xml:id="struct-388317" status="OLD">
          <orgName>Techniques pour l'Evaluation et la Modélisation des Actions de la Santé</orgName>
          <orgName type="acronym">TIMC-IMAG-ThEMAS</orgName>
          <date type="end">2015-12-31</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www-timc.imag.fr/ThEMAS</ref>
          </desc>
          <listRelation>
            <relation active="#struct-707" type="direct"/>
            <relation active="#struct-51016" type="indirect"/>
            <relation active="#struct-89889" type="indirect"/>
            <relation active="#struct-301767" type="indirect"/>
            <relation name="UMR5525" active="#struct-441569" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-356603" status="VALID">
          <orgName>Centre Hospitalier Régional Universitaire de Brest</orgName>
          <orgName type="acronym">CHRU Brest</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-707" status="OLD">
          <idno type="IdRef">14728936X</idno>
          <idno type="ISNI">0000 0004 4687 1979</idno>
          <idno type="RNSR">199511969L</idno>
          <idno type="ROR">https://ror.org/03985kf35</idno>
          <orgName>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525</orgName>
          <orgName type="acronym">TIMC-IMAG</orgName>
          <date type="start">1993-01-01</date>
          <date type="end">2015-12-31</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www-timc.imag.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-51016" type="direct"/>
            <relation active="#struct-89889" type="direct"/>
            <relation active="#struct-301767" type="direct"/>
            <relation name="UMR5525" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-51016" status="OLD">
          <idno type="IdRef">026404796</idno>
          <idno type="ROR">https://ror.org/02aj0kh94</idno>
          <orgName>Université Joseph Fourier - Grenoble 1</orgName>
          <orgName type="acronym">UJF</orgName>
          <date type="end">2015-12-31</date>
          <desc>
            <address>
              <addrLine>BP 53 - 38041 Grenoble Cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ujf-grenoble.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-89889" status="OLD">
          <idno type="IdRef">026388804</idno>
          <idno type="ROR">https://ror.org/05sbt2524</idno>
          <orgName>Institut polytechnique de Grenoble - Grenoble Institute of Technology</orgName>
          <orgName type="acronym">Grenoble INP</orgName>
          <date type="start">2007-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>46 avenue Félix Viallet 38031 Grenoble Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.grenoble-inp.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301767" status="VALID">
          <idno type="ROR">https://ror.org/01c7wz417</idno>
          <orgName>VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement</orgName>
          <orgName type="acronym">VAS</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Lyon, VetAgro Sup, 69280 Marcy l'Etoile (campus vétérinaire); Université de Clermont, VetAgro Sup, 63370 Lempdes (campus agronomique)</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.vetagro-sup.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>