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Article Dans Une Revue Molecular Ecology Année : 2010

In defence of model-based inference in phylogeography.

Mark A Beaumont
  • Fonction : Auteur
Rasmus Nielsen
  • Fonction : Auteur
Jody Hey
  • Fonction : Auteur
Oscar Gaggiotti
  • Fonction : Auteur
Lacey Knowles
  • Fonction : Auteur
Mahesh Panchal
  • Fonction : Auteur
Jukka Corander
  • Fonction : Auteur
Mike Hickerson
  • Fonction : Auteur
Scott A Sisson
  • Fonction : Auteur
Nelson Fagundes
  • Fonction : Auteur
Lounès Chikhi
Peter Beerli
  • Fonction : Auteur
John Huelsenbeck
  • Fonction : Auteur
Matthieu Foll
Ziheng Yang
David Balding
  • Fonction : Auteur
Laurent Excoffier

Résumé

Recent papers have promoted the view that model-based methods in general, and those based on Approximate Bayesian Computation (ABC) in particular, are flawed in a number of ways, and are therefore inappropriate for the analysis of phylogeographic data. These papers further argue that Nested Clade Phylogeographic Analysis (NCPA) offers the best approach in statistical phylogeography. In order to remove the confusion and misconceptions introduced by these papers, we justify and explain the reasoning behind model-based inference. We argue that ABC is a statistically valid approach, alongside other computational statistical techniques that have been successfully used to infer parameters and compare models in population genetics. We also examine the NCPA method and highlight numerous deficiencies, either when used with single or multiple loci. We further show that the ages of clades are carelessly used to infer ages of demographic events, that these ages are estimated under a simple model of panmixia and population stationarity but are then used under different and unspecified models to test hypotheses, a usage the invalidates these testing procedures. We conclude by encouraging researchers to study and use model-based inference in population genetics.

Dates et versions

hal-00450030 , version 1 (25-01-2010)

Identifiants

Citer

Mark A Beaumont, Rasmus Nielsen, Christian P. Robert, Jody Hey, Oscar Gaggiotti, et al.. In defence of model-based inference in phylogeography.. Molecular Ecology, 2010, 19 (3), epub ahead of print. ⟨10.1111/j.1365-294X.2009.04515.x⟩. ⟨hal-00450030⟩
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