On the regularization of singular c-optimal designs
Résumé
We consider the design of c-optimal experiments for the estimation of a scalar function h(t) of the parameters t in a nonlinear regression model. A c-optimal design x* may be singular, and we derive conditions ensuring the asymptotic normality of the Least-Squares estimator of h(t) for a singular design over a finite space. As illustrated by an example, the singular designs for which asymptotic normality holds typically depend on the unknown true value of t, which makes singular c-optimal designs of no practical use in nonlinear situations. Some simple alternatives are then suggested for constructing nonsingular designs that approach a c-optimal design under some conditions.
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