Three-dimensional (3-D) tomographic images of a nodular graphite cast iron obtained using a laboratory X-ray source were used to analyze the opening of a fatigue crack during in situ mechanical loading. Direct image analysis and digital image correlation are utilized to obtain the 3-D morphology and front location of the crack, as well as the displacement fields in the bulk of the specimen. From digital image correlation results it is possible to extract the crack opening displacement (COD) map in the whole sample cross-section and to compute stress intensity factors (SIFs) all along the crack front, even for COD values that are less than the image resolution. The comparison of COD maps with local values of the SIF enabled for an estimation of the opening SIF (Kop) equal to 6 MPa m^(1/2).