Chapter 6 stereocontrolled synthesis of mannans and rhamnans.
Résumé
The total synthesis of the alpha-mannans, alpha-rhamnans, beta-mannans, and beta-rhamnans is presented according to the overall strategy employed. The alpha-mannans and alpha-rhamnans are discussed in terms of the use of use or not of neighboring-group participation to construct the 1,2-trans-axial glycosidic bond, whereas the beta-mannan and beta-rhamnan syntheses are classified as either direct or indirect, with the latter requiring additional steps post-glycosylation to achieve the 1,2-cis-equatorial glycosidic linkage.