In this paper a modified two-dimensional Luikov model for evaluating the non-isothermal moisture migration in porous building materials was proposed. The coupled heat and moisture transfer problem was modeled. Vapor content and temperature were chosen as the principal driving potentials. The coupled equations were solved by a numerical method, which consists of a finite difference technique with a fully implicit scheme in time. Two validation experiments were developed in this study. The evolution of transient moisture distributions in both one-dimensional and two-dimensional cases was measured. A comparison between experimental results and those obtained by the numerical model proves that they are fully consistent with each other. The modified model can be integrated into a whole building heat, air and moisture transfer model.