Rewriting game theory as a foundation for sate-based models of gene regulation - Archive ouverte HAL
Communication Dans Un Congrès Année : 2006

Rewriting game theory as a foundation for sate-based models of gene regulation

Résumé

We present a game-theoretic foundation for gene regulatory analysis based on the recent formalism of rewriting game theory. Rewrit- ing game theory is discrete and comes with a graph-based framework for understanding compromises and interactions between players and for computing Nash equilibria. The formalism explicitly represents the dy- namics of its Nash equilibria and, therefore, is a suitable foundation for the study of steady states in discrete modelling. We apply the formalism to the discrete analysis of gene regulatory networks introduced by R. Thomas and S. Kauffman. Specifically, we show that their models are specific instances of a C/P game deduced from the K parameter.
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hal-00339800 , version 1 (18-08-2022)

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Chafika Chettaoui, Franck Delaplace, Pierre Lescanne, Mun'delanji Vestergaard, René Vestergaard. Rewriting game theory as a foundation for sate-based models of gene regulation. International Conference on Computational Methods in Systems Biology (CMSB 2006), Oct 2006, Trento, Italy. pp.257-270, ⟨10.1007/11885191_18⟩. ⟨hal-00339800⟩
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