Land-use change and climate change, along with groundwater pumping are frequently indicated to be the main human-induced factors influencing the groundwater system. Up till now, research has mainly been focusing on the effect of the water quality of these human-induced changes on the groundwater system, often neglecting changes in quantity. The focus in this study is on the impact of land-use changes in the near future, from 2000 until 2020, on the groundwater quantity and the general hydrologic balance of a sub-catchment of the Kleine Nete, Belgium. This study tests a new methodology which involves coupling a land-use change model with a water balance model and a groundwater model. The future land-use is modelled with the CLUE-S model. Four scenarios (A1, A2, B1 and B2) based on the Special Report on Emission Scenarios (SRES) are used for the land-use modelling. Water balance components, groundwater level and baseflow are simulated using the WetSpass model in conjunction with a MODFLOW groundwater model. Results show that the average recharge slowly decreases for all scenarios, the decreases are 2.9, 1.6, 1.8 and 0.8% for respectively scenario A1, A2, B1 and B2. The predicted reduction in recharge results in a small decrease of the average groundwater level, ranging from 2.5 cm for scenario A1 to 0.9 cm for scenario B2, and a reduction of the total baseflow with maximum 2.3% and minimum 0.7% respectively for scenario A1 and B2. Although these average values do not indicate significant changes for the groundwater system, spatial analysis of the changes shows the changes are concentrated in the neighbourhood of the major cities in the study areas. It is therefore important for spatial managers to take the groundwater system into account for reducing the negative impacts of land-use and climate change as much as possible.