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Article Dans Une Revue NeuroReport Année : 2004

RNA-binding proteins and neural development: a matter of targets and complexes.

Résumé

RNA-binding proteins control multiple steps of nuclear and cytoplasmic RNA processing including alternative splicing, stabilization, transport and translational repression of RNAs. Here we present existing evidence showing that RNA-binding proteins expressed in the nervous system are required in many steps of its development and play multiple roles during the life of a neuron. We describe emerging views based on recent studies strongly suggesting that RNA-binding proteins cooperate actively within neurons in large multifunctional complexes to regulate the flow of information encoded in ribonomes in a coordinated fashion.
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Dates et versions

hal-00283594 , version 1 (30-05-2008)

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  • HAL Id : hal-00283594 , version 1
  • PUBMED : 15570153

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François Agnès, Muriel Perron. RNA-binding proteins and neural development: a matter of targets and complexes.. NeuroReport, 2004, 15 (17), pp.2567-70. ⟨hal-00283594⟩
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