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Journal Articles Science Year : 2007

The Chlamydomonas genome reveals the evolution of key animal and plant functions.

Sabeeha S Merchant (1) , Simon E Prochnik (2) , Olivier Vallon (3) , Elizabeth H Harris (4) , Steven J Karpowicz (1) , George B Witman (5) , Astrid Terry (2) , Asaf Salamov (2) , Lillian K Fritz-Laylin (6) , Laurence Maréchal-Drouard (7) , Wallace F Marshall (8) , Liang-Hu Qu (9) , David R Nelson (10) , Anton A Sanderfoot (11) , Martin H Spalding (12) , Vladimir V Kapitonov (13) , Qinghu Ren (14) , Patrick Ferris (15) , Erika Lindquist (2) , Harris Shapiro (2) , Susan M Lucas (2) , Jane Grimwood (16) , Jeremy Schmutz (16) , Pierre Cardol (3, 17) , Heriberto Cerutti (18) , Guillaume Chanfreau (1) , Chun-Long Chen (9) , Valérie Cognat (7) , Martin T Croft (19) , Rachel Dent (20) , Susan Dutcher (21) , Emilio Fernández (22) , Hideya Fukuzawa (23) , David González-Ballester (24) , Diego González-Halphen (25) , Armin Hallmann (26) , Marc Hanikenne (17) , Michael Hippler (27) , William Inwood (20) , Kamel Jabbari (28) , Ming Kalanon (29) , Richard Kuras (3) , Paul A Lefebvre (11) , Stéphane D Lemaire (30) , Alexey V Lobanov (31) , Martin Lohr (32) , Andrea Manuell (33) , Iris Meier (34) , Laurens Mets (35) , Maria Mittag (36) , Telsa Mittelmeier (37) , James V Moroney (38) , Jeffrey Moseley (24) , Carolyn Napoli (39) , Aurora M Nedelcu (40) , Krishna Niyogi (20) , Sergey V Novoselov (31) , Ian T Paulsen (14) , Greg Pazour (41) , Saul Purton (42) , Jean-Philippe Ral (43) , Diego Mauricio Riaño-Pachón (44) , Wayne Riekhof (45) , Linda Rymarquis (46) , Michael Schroda (47) , David L. Stern (48) , James Umen (15) , Robert Willows (49) , Nedra Wilson (50) , Sara Lana Zimmer (48) , Jens Allmer (51) , Janneke Balk (19) , Katerina Bisova (52) , Chong-Jian Chen (9) , Marek Elias (53) , Karla Gendler (39) , Charles Hauser (54) , Mary Rose Lamb (55) , Heidi Ledford (20) , Joanne C Long (1) , Jun Minagawa (56) , M Dudley Page (1) , Junmin Pan (57) , Wirulda Pootakham (24) , Sanja Roje (58) , Annkatrin Rose (59) , Eric Stahlberg (34) , Aimee M Terauchi (1) , Pinfen Yang (60) , Steven Ball (43) , Chris Bowler (28, 61) , Carol L Dieckmann (37) , Vadim N Gladyshev (31) , Pamela Green (46) , Richard Jorgensen (39) , Stephen Mayfield (33) , Bernd Mueller-Roeber (44) , Sathish Rajamani (62) , Richard T Sayre (34) , Peter Brokstein (2) , Inna Dubchak (2) , David Goodstein (2) , Leila Hornick (2) , y Wayne Huang (2) , Jinal Jhaveri (2) , Yigong Luo (2) , Diego Martínez (2) , Wing Chi Abby Ngau (2) , Bobby Otillar (2) , Alexander Poliakov (2) , Aaron Porter (2) , Lukasz Szajkowski (2) , Gregory Werner (2) , Kemin Zhou (2) , Igor V Grigoriev (2) , Daniel S Rokhsar (2, 6) , Arthur R Grossman (24)
1 Department of Chemistry and Biochemistry
2 DOE - Department of Energy / Joint Genome Institute
3 PMMC - Physiologie membranaire et moléculaire du chloroplaste
4 Department of Biology
5 Department of Cell Biology
6 Department of Molecular & Cell Biology [Berkeley]
7 IBMP - Institut de Biologie Moléculaire des Plantes
8 Department of Biochemistry and Biophysics
9 Biotechnology Research Center
10 Department of Molecular Sciences and Center of Excellence in Genomics and Bioinformatics
11 Department of Plant Biology
12 Department of Genetics, Development, and Cell Biology
13 GIRI - Genetic Information Research Institute
14 TIGR - The Institute for Genomic Research
15 Plant Biology Laboratory
16 Stanford School of Medicine [Stanford]
17 Plant Biology Institute, Department of Life Sciences
18 School of Biological Sciences–Plant Science Initiative
19 Department of Plant Sciences
20 Department of Plant and Microbial Biology [Berkeley]
21 Department of Genetics
22 Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias
23 Graduate School of Biostudies
24 DPB - Department of Plant Biology [Carnegie]
25 Departamento de Genética Molecular, Instituto de Fisiología Celular
26 Department of Cellular and Developmental Biology of Plants
27 Institute for Plant Biochemistry and Biotechnology
28 IJM (UMR_7592) - Institut Jacques Monod
29 Plant Cell Biology Research Centre, The School of Botany
30 IBP - Institut de biotechnologie des plantes
31 Department of Biochemistry
32 Institut für Allgemeine Botanik
33 Department of Cell Biology and Skaggs Institute for Chemical Biology
34 PCMB and Plant Biotechnology Center
35 Molecular Genetics and Cell Biology
36 Institut für Allgemeine Botanik und Pflanzenphysiologie
37 Department of Molecular and Cellular Biology [University of Arizona]
38 Department of Biological Science
39 Biology Institute
40 Department of Biology
41 Department of Physiology
42 Department of Biology
43 UGSF - Unité de Glycobiologie Structurale et Fonctionnelle - UMR 8576
44 University of Potsdam = Universität Potsdam
45 Department of Medicine
46 Delaware Biotechnology Institute
47 Institute of Biology II/Plant Biochemistry
48 Boyce Thompson Institute [Ithaca]
49 Department of Chemistry and Biomolecular Sciences
50 Department of Anatomy and Cell Biology
51 Izmir Ekonomi Universitesi
52 Institute of Microbiology
53 Department of Plant Physiology, Faculty of Sciences
54 Bioinformatics Program
55 Department of Biology
56 Institute of Low-Temperature Science
57 Department of Biology
58 Institute of Biological Chemistry
59 Appalachian State University
60 Department of Biology
61 Cell Signaling Laboratory
62 Graduate Program in Biophysics
Chun-Long Chen
Kamel Jabbari
  • Function : Author
  • PersonId : 911237
Carolyn Napoli
  • Function : Author
Karla Gendler
  • Function : Author
Jun Minagawa
Junmin Pan
  • Function : Author
Chris Bowler

Abstract

Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the approximately 120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella.

Dates and versions

hal-00198837 , version 1 (18-12-2007)

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Sabeeha S Merchant, Simon E Prochnik, Olivier Vallon, Elizabeth H Harris, Steven J Karpowicz, et al.. The Chlamydomonas genome reveals the evolution of key animal and plant functions.. Science, 2007, 318 (5848), pp.245-50. ⟨10.1126/science.1143609⟩. ⟨hal-00198837⟩
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