Journal Articles Infection and Immunity Year : 2005

High susceptibility of human dendritic cells to invasion by the intracellular pathogens Brucella suis, B. abortus, and B. melitensis.

Abstract

Bacteria from the Brucella genus are able to survive and proliferate within macrophages. Because they are phylogenetically closely related to macrophages, myeloid dendritic cells (DCs) constitute potential targets for Brucella bacteria. Here we report that DCs display a great susceptibility to Brucella infection. Therefore, DCs might serve as a reservoir and be important for the development of Brucella bacteria within their host.

Dates and versions

hal-00194021 , version 1 (05-12-2007)

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Elisabeth Billard, Chantal Cazevieille, Jacques Dornand, Antoine Gross. High susceptibility of human dendritic cells to invasion by the intracellular pathogens Brucella suis, B. abortus, and B. melitensis.. Infection and Immunity, 2005, 73 (12), pp.8418-24. ⟨10.1128/IAI.73.12.8418-8424.2005⟩. ⟨hal-00194021⟩

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