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Journal Articles Science Year : 2003

The needle length of bacterial injectisomes is determined by a molecular ruler.

Laure Journet
Guy R Cornelis
  • Function : Correspondent author
  • PersonId : 843231

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Abstract

Size determination represents a fundamental requirement for multicomponent biological structures. Some pathogenic bacteria possess a weapon derived from the flagellum. Like the flagellum, this type-III secretion apparatus, called the injectisome, has a transmembrane basal body, but the external component is a needle-like structure instead of a hook and a filament. Here, we provide evidence that the length of this needle is determined by the size of a protein, YscP, acting as a molecular ruler.
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hal-00177660 , version 1 (08-10-2007)

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Laure Journet, Céline Agrain, Petr Broz, Guy R Cornelis. The needle length of bacterial injectisomes is determined by a molecular ruler.. Science, 2003, 302 (5651), pp.1757-60. ⟨10.1126/science.1091422⟩. ⟨hal-00177660⟩
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