<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-00174474</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-22T17:54:01+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes</title>
            <author role="aut">
              <persName>
                <forename type="first">David</forename>
                <surname>Meyre</surname>
              </persName>
              <email type="md5">27e8d815623034404e6b0550e8ae9b06</email>
              <email type="domain">mcmaster.ca</email>
              <idno type="idhal" notation="numeric">756908</idno>
              <idno type="halauthorid" notation="string">160321-756908</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-4850-7444</idno>
              <affiliation ref="#struct-1238"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Nabila</forename>
                <surname>Bouatia-Naji</surname>
              </persName>
              <email type="md5">2eb5b2dbd94be54953055e63ad2540d3</email>
              <email type="domain">inserm.fr</email>
              <idno type="idhal" notation="numeric">1056906</idno>
              <idno type="halauthorid" notation="string">228819-1056906</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-5424-2134</idno>
              <idno type="IDREF">https://www.idref.fr/112489354</idno>
              <affiliation ref="#struct-300166"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Agnès</forename>
                <surname>Tounian</surname>
              </persName>
              <idno type="halauthorid">230258-0</idno>
              <affiliation ref="#struct-306007"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Chantal</forename>
                <surname>Samson</surname>
              </persName>
              <idno type="halauthorid">190003-0</idno>
              <affiliation ref="#struct-1238"/>
              <affiliation ref="#struct-93488"/>
              <affiliation ref="#struct-26889"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Cécile</forename>
                <surname>Lecoeur</surname>
              </persName>
              <idno type="halauthorid">159242-0</idno>
              <affiliation ref="#struct-1238"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Vincent</forename>
                <surname>Vatin</surname>
              </persName>
              <idno type="halauthorid">160146-0</idno>
              <affiliation ref="#struct-1238"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Maya</forename>
                <surname>Ghoussaini</surname>
              </persName>
              <idno type="halauthorid">160320-0</idno>
              <affiliation ref="#struct-1238"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Christophe</forename>
                <surname>Wachter</surname>
              </persName>
              <idno type="halauthorid">230259-0</idno>
              <affiliation ref="#struct-300166"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Serge</forename>
                <surname>Hercberg</surname>
              </persName>
              <email type="md5">622cb98f67075610f3fa82734e3628f7</email>
              <email type="domain">uren.smbh.univ-paris13.fr</email>
              <idno type="idhal" notation="numeric">1136672</idno>
              <idno type="halauthorid" notation="string">160152-1136672</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-3168-1350</idno>
              <idno type="IDREF">https://www.idref.fr/02858709X</idno>
              <affiliation ref="#struct-235755"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Guillaume</forename>
                <surname>Charpentier</surname>
              </persName>
              <email type="md5">e5db9f2c0ea72f058f8960224cf83e92</email>
              <email type="domain">free.fr</email>
              <idno type="idhal" notation="numeric">911464</idno>
              <idno type="halauthorid" notation="string">159245-911464</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-6124-5712</idno>
              <affiliation ref="#struct-184952"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Wolfgang</forename>
                <surname>Patsch</surname>
              </persName>
              <idno type="halauthorid">229558-0</idno>
              <affiliation ref="#struct-530598"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">François</forename>
                <surname>Pattou</surname>
              </persName>
              <email type="md5">ce67ab0f13ca6d41a10273b6195ab21b</email>
              <email type="domain">univ-lille.fr</email>
              <idno type="idhal" notation="numeric">758667</idno>
              <idno type="halauthorid" notation="string">229550-758667</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-8388-3766</idno>
              <idno type="IDREF">https://www.idref.fr/074750364</idno>
              <affiliation ref="#struct-303623"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Marie-Aline</forename>
                <surname>Charles</surname>
              </persName>
              <email type="md5">16edfe3df4399f400535fe8364f99844</email>
              <email type="domain">inserm.fr</email>
              <idno type="idhal" notation="string">marie-aline-charles</idno>
              <idno type="idhal" notation="numeric">756717</idno>
              <idno type="halauthorid" notation="string">153662-756717</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-4025-4390</idno>
              <idno type="IDREF">https://www.idref.fr/095063277</idno>
              <affiliation ref="#struct-2857"/>
              <affiliation ref="#struct-531"/>
              <affiliation ref="#struct-2807"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Patrick</forename>
                <surname>Tounian</surname>
              </persName>
              <email type="md5">05ce9e0832cb34f25b72bbf87dbef1a7</email>
              <email type="domain">aphp.fr</email>
              <idno type="idhal" notation="numeric">1114473</idno>
              <idno type="halauthorid" notation="string">228880-1114473</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-2138-6702</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-5976-2240</idno>
              <affiliation ref="#struct-360410"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Karine</forename>
                <surname>Clément</surname>
              </persName>
              <email type="md5">8cecb3bb1647a3a11b8432891e78cbad</email>
              <email type="domain">aphp.fr</email>
              <idno type="idhal" notation="numeric">756892</idno>
              <idno type="halauthorid" notation="string">160147-756892</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-2489-3355</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-4619-6785</idno>
              <idno type="IDREF">https://www.idref.fr/07341512X</idno>
              <idno type="VIAF">https://viaf.org/viaf/85252154</idno>
              <idno type="ISNI">http://isni.org/isni/0000000114764536</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/GAJ-5747-2022</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/R-1120-2017</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/GAJ-5747-2022</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/R-1120-2017</idno>
              <affiliation ref="#struct-1238"/>
              <affiliation ref="#struct-18903"/>
              <affiliation ref="#struct-99711"/>
              <affiliation ref="#struct-11965"/>
              <affiliation ref="#struct-28185"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Béatrice</forename>
                <surname>Jouret</surname>
              </persName>
              <idno type="halauthorid">228878-0</idno>
              <affiliation ref="#struct-303623"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jacques</forename>
                <surname>Weill</surname>
              </persName>
              <idno type="halauthorid">160324-0</idno>
              <affiliation ref="#struct-18944"/>
              <affiliation ref="#struct-1142"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Betty A</forename>
                <surname>Maddux</surname>
              </persName>
              <idno type="halauthorid">230260-0</idno>
              <affiliation ref="#struct-190541"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Ira D</forename>
                <surname>Goldfine</surname>
              </persName>
              <idno type="halauthorid">230261-0</idno>
              <affiliation ref="#struct-190541"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Andrew</forename>
                <surname>Walley</surname>
              </persName>
              <idno type="halauthorid">230122-0</idno>
              <affiliation ref="#struct-69530"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Philippe</forename>
                <surname>Boutin</surname>
              </persName>
              <idno type="halauthorid">160155-0</idno>
              <affiliation ref="#struct-1238"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Christian</forename>
                <surname>Dina</surname>
              </persName>
              <email type="md5">0fbcdda7b110798f353c599d201329f7</email>
              <email type="domain">good.ibl.fr</email>
              <idno type="idhal" notation="numeric">756757</idno>
              <idno type="halauthorid" notation="string">154896-756757</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-7722-7348</idno>
              <idno type="IDREF">https://www.idref.fr/185866557</idno>
              <affiliation ref="#struct-1238"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Philippe</forename>
                <surname>Froguel</surname>
              </persName>
              <email type="md5">e3a7bff8517ce0850f8fbc4a6b8ece30</email>
              <email type="domain">good.ibl.fr</email>
              <idno type="idhal" notation="numeric">1315149</idno>
              <idno type="halauthorid" notation="string">154897-1315149</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-2972-0784</idno>
              <affiliation ref="#struct-1238"/>
              <affiliation ref="#struct-18570"/>
              <affiliation ref="#struct-18946"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Philippe</forename>
                <surname>Froguel</surname>
              </persName>
              <email type="md5">e3a7bff8517ce0850f8fbc4a6b8ece30</email>
              <email type="domain">good.ibl.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2022-01-25 15:41:14</date>
              <date type="whenModified">2026-04-01 03:13:25</date>
              <date type="whenReleased">2022-02-07 08:27:11</date>
              <date type="whenProduced">2005-08</date>
              <date type="whenEndEmbargoed">2022-01-25</date>
              <ref type="file" target="https://hal.science/hal-00174474v1/document">
                <date notBefore="2022-01-25"/>
              </ref>
              <ref type="file" subtype="author" n="1" target="https://hal.science/hal-00174474v1/file/nihms4824.pdf" id="file-3542798-3101970">
                <date notBefore="2022-01-25"/>
              </ref>
              <ref type="externalLink" target="https://europepmc.org/articles/pmc2000804?pdf=render"/>
              <fs>
                <f name="inra_publicVise_local" notation="string" n="SC">
                  <string>inra_publicVise_local_SC</string>
                </f>
              </fs>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="112917">
                <persName>
                  <forename>Philippe</forename>
                  <surname>Froguel</surname>
                </persName>
                <email type="md5">e3a7bff8517ce0850f8fbc4a6b8ece30</email>
                <email type="domain">good.ibl.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-00174474</idno>
            <idno type="halUri">https://hal.science/hal-00174474</idno>
            <idno type="halBibtex">meyre:hal-00174474</idno>
            <idno type="halRefHtml">&lt;i&gt;Nature Genetics&lt;/i&gt;, 2005, 37 (8), pp.863-7. &lt;a target="_blank" href="https://dx.doi.org/10.1038/ng1604"&gt;&amp;#x27E8;10.1038/ng1604&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Nature Genetics, 2005, 37 (8), pp.863-7. &amp;#x27E8;10.1038/ng1604&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://about.hal.science/hal-authorisation-v1/">HAL Authorization<ref corresp="#file-3542798-3101970"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="RIIP">Pasteur Network</idno>
            <idno type="stamp" n="UNIV-PARIS13">Université Paris-Nord - Paris XIII </idno>
            <idno type="stamp" n="UPMC" corresp="SORBONNE-UNIVERSITE">Université Pierre et Marie Curie</idno>
            <idno type="stamp" n="ESPCI">ESPCI Paris-PSL</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-PSUD">Université Paris Sud - Paris XI</idno>
            <idno type="stamp" n="CNAM">Conservatoire National des Arts et Métiers</idno>
            <idno type="stamp" n="INRA">INRA - Institut national de la recherche agronomique</idno>
            <idno type="stamp" n="IFR69" corresp="INSERM">IFR69</idno>
            <idno type="stamp" n="IFR58" corresp="INSERM">Les cordeliers</idno>
            <idno type="stamp" n="APHP" corresp="INSERM">AP-HP</idno>
            <idno type="stamp" n="RIIP_LILLE" corresp="RIIP">Institut Pasteur de Lille</idno>
            <idno type="stamp" n="PARISTECH">ParisTech</idno>
            <idno type="stamp" n="PSL">Université Paris sciences et lettres</idno>
            <idno type="stamp" n="UNIV-PARIS-SACLAY">Université Paris-Saclay</idno>
            <idno type="stamp" n="AGREENIUM">Archive ouverte en agrobiosciences</idno>
            <idno type="stamp" n="UNIV-PSUD-SACLAY" corresp="UNIV-PARIS-SACLAY">Université Paris Sud pour Paris Saclay</idno>
            <idno type="stamp" n="EREN" corresp="UNIV-PARIS13">Équipe de recherche en épidémiologie nutritionnelle</idno>
            <idno type="stamp" n="INSHEA" corresp="UNIV-PARIS-LUMIERES">INSEI - Institut national supérieur de formation et de recherche pour l'éducation inclusive</idno>
            <idno type="stamp" n="CHU-UNIV-PARIS5">Les centres hospitaliers de Paris Descartes</idno>
            <idno type="stamp" n="SORBONNE-UNIVERSITE">Sorbonne Université</idno>
            <idno type="stamp" n="SU-INF-2018" corresp="SORBONNE-UNIVERSITE">SORBONNE université &lt;2018</idno>
            <idno type="stamp" n="SU-MEDECINE" corresp="SORBONNE-UNIVERSITE">Faculté de Santé de Sorbonne Université</idno>
            <idno type="stamp" n="SU-SCIENCES" corresp="SORBONNE-UNIVERSITE">Faculté des Sciences de Sorbonne Université</idno>
            <idno type="stamp" n="SU-MED" corresp="SORBONNE-UNIVERSITE">Médecine - Sorbonne Université</idno>
            <idno type="stamp" n="SU-SCI" corresp="SORBONNE-UNIVERSITE">Sciences - Sorbonne Université</idno>
            <idno type="stamp" n="UNIV-PARIS-LUMIERES"/>
            <idno type="stamp" n="IBHGC" corresp="UNIV-PARIS13">Institut de Biomécanique Humaine Georges Charpak</idno>
            <idno type="stamp" n="INRAE">Institut National de Recherche en Agriculture, Alimentation et Environnement</idno>
            <idno type="stamp" n="SORBONNE-PARIS-NORD">Université Sorbonne Paris Nord</idno>
            <idno type="stamp" n="ESPCI-PSL" corresp="PSL">Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris - PSL</idno>
            <idno type="stamp" n="SU-TI">Sorbonne Université - Texte Intégral</idno>
            <idno type="stamp" n="ALLIANCE-SU"> Alliance Sorbonne Université</idno>
            <idno type="stamp" n="ACT-R" corresp="UNIV-PARIS13">Act'R </idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="1">Not set</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes</title>
                <author role="aut">
                  <persName>
                    <forename type="first">David</forename>
                    <surname>Meyre</surname>
                  </persName>
                  <email type="md5">27e8d815623034404e6b0550e8ae9b06</email>
                  <email type="domain">mcmaster.ca</email>
                  <idno type="idhal" notation="numeric">756908</idno>
                  <idno type="halauthorid" notation="string">160321-756908</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-4850-7444</idno>
                  <affiliation ref="#struct-1238"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Nabila</forename>
                    <surname>Bouatia-Naji</surname>
                  </persName>
                  <email type="md5">2eb5b2dbd94be54953055e63ad2540d3</email>
                  <email type="domain">inserm.fr</email>
                  <idno type="idhal" notation="numeric">1056906</idno>
                  <idno type="halauthorid" notation="string">228819-1056906</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-5424-2134</idno>
                  <idno type="IDREF">https://www.idref.fr/112489354</idno>
                  <affiliation ref="#struct-300166"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Agnès</forename>
                    <surname>Tounian</surname>
                  </persName>
                  <idno type="halauthorid">230258-0</idno>
                  <affiliation ref="#struct-306007"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Chantal</forename>
                    <surname>Samson</surname>
                  </persName>
                  <idno type="halauthorid">190003-0</idno>
                  <affiliation ref="#struct-1238"/>
                  <affiliation ref="#struct-93488"/>
                  <affiliation ref="#struct-26889"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Cécile</forename>
                    <surname>Lecoeur</surname>
                  </persName>
                  <idno type="halauthorid">159242-0</idno>
                  <affiliation ref="#struct-1238"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Vincent</forename>
                    <surname>Vatin</surname>
                  </persName>
                  <idno type="halauthorid">160146-0</idno>
                  <affiliation ref="#struct-1238"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Maya</forename>
                    <surname>Ghoussaini</surname>
                  </persName>
                  <idno type="halauthorid">160320-0</idno>
                  <affiliation ref="#struct-1238"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Christophe</forename>
                    <surname>Wachter</surname>
                  </persName>
                  <idno type="halauthorid">230259-0</idno>
                  <affiliation ref="#struct-300166"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Serge</forename>
                    <surname>Hercberg</surname>
                  </persName>
                  <email type="md5">622cb98f67075610f3fa82734e3628f7</email>
                  <email type="domain">uren.smbh.univ-paris13.fr</email>
                  <idno type="idhal" notation="numeric">1136672</idno>
                  <idno type="halauthorid" notation="string">160152-1136672</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-3168-1350</idno>
                  <idno type="IDREF">https://www.idref.fr/02858709X</idno>
                  <affiliation ref="#struct-235755"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Guillaume</forename>
                    <surname>Charpentier</surname>
                  </persName>
                  <email type="md5">e5db9f2c0ea72f058f8960224cf83e92</email>
                  <email type="domain">free.fr</email>
                  <idno type="idhal" notation="numeric">911464</idno>
                  <idno type="halauthorid" notation="string">159245-911464</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-6124-5712</idno>
                  <affiliation ref="#struct-184952"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Wolfgang</forename>
                    <surname>Patsch</surname>
                  </persName>
                  <idno type="halauthorid">229558-0</idno>
                  <affiliation ref="#struct-530598"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">François</forename>
                    <surname>Pattou</surname>
                  </persName>
                  <email type="md5">ce67ab0f13ca6d41a10273b6195ab21b</email>
                  <email type="domain">univ-lille.fr</email>
                  <idno type="idhal" notation="numeric">758667</idno>
                  <idno type="halauthorid" notation="string">229550-758667</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-8388-3766</idno>
                  <idno type="IDREF">https://www.idref.fr/074750364</idno>
                  <affiliation ref="#struct-303623"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Marie-Aline</forename>
                    <surname>Charles</surname>
                  </persName>
                  <email type="md5">16edfe3df4399f400535fe8364f99844</email>
                  <email type="domain">inserm.fr</email>
                  <idno type="idhal" notation="string">marie-aline-charles</idno>
                  <idno type="idhal" notation="numeric">756717</idno>
                  <idno type="halauthorid" notation="string">153662-756717</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-4025-4390</idno>
                  <idno type="IDREF">https://www.idref.fr/095063277</idno>
                  <affiliation ref="#struct-2857"/>
                  <affiliation ref="#struct-531"/>
                  <affiliation ref="#struct-2807"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Patrick</forename>
                    <surname>Tounian</surname>
                  </persName>
                  <email type="md5">05ce9e0832cb34f25b72bbf87dbef1a7</email>
                  <email type="domain">aphp.fr</email>
                  <idno type="idhal" notation="numeric">1114473</idno>
                  <idno type="halauthorid" notation="string">228880-1114473</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-2138-6702</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-5976-2240</idno>
                  <affiliation ref="#struct-360410"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Karine</forename>
                    <surname>Clément</surname>
                  </persName>
                  <email type="md5">8cecb3bb1647a3a11b8432891e78cbad</email>
                  <email type="domain">aphp.fr</email>
                  <idno type="idhal" notation="numeric">756892</idno>
                  <idno type="halauthorid" notation="string">160147-756892</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-2489-3355</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-4619-6785</idno>
                  <idno type="IDREF">https://www.idref.fr/07341512X</idno>
                  <idno type="VIAF">https://viaf.org/viaf/85252154</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000114764536</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/GAJ-5747-2022</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/R-1120-2017</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/GAJ-5747-2022</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/R-1120-2017</idno>
                  <affiliation ref="#struct-1238"/>
                  <affiliation ref="#struct-18903"/>
                  <affiliation ref="#struct-99711"/>
                  <affiliation ref="#struct-11965"/>
                  <affiliation ref="#struct-28185"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Béatrice</forename>
                    <surname>Jouret</surname>
                  </persName>
                  <idno type="halauthorid">228878-0</idno>
                  <affiliation ref="#struct-303623"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jacques</forename>
                    <surname>Weill</surname>
                  </persName>
                  <idno type="halauthorid">160324-0</idno>
                  <affiliation ref="#struct-18944"/>
                  <affiliation ref="#struct-1142"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Betty A</forename>
                    <surname>Maddux</surname>
                  </persName>
                  <idno type="halauthorid">230260-0</idno>
                  <affiliation ref="#struct-190541"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Ira D</forename>
                    <surname>Goldfine</surname>
                  </persName>
                  <idno type="halauthorid">230261-0</idno>
                  <affiliation ref="#struct-190541"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Andrew</forename>
                    <surname>Walley</surname>
                  </persName>
                  <idno type="halauthorid">230122-0</idno>
                  <affiliation ref="#struct-69530"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Philippe</forename>
                    <surname>Boutin</surname>
                  </persName>
                  <idno type="halauthorid">160155-0</idno>
                  <affiliation ref="#struct-1238"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Christian</forename>
                    <surname>Dina</surname>
                  </persName>
                  <email type="md5">0fbcdda7b110798f353c599d201329f7</email>
                  <email type="domain">good.ibl.fr</email>
                  <idno type="idhal" notation="numeric">756757</idno>
                  <idno type="halauthorid" notation="string">154896-756757</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-7722-7348</idno>
                  <idno type="IDREF">https://www.idref.fr/185866557</idno>
                  <affiliation ref="#struct-1238"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Philippe</forename>
                    <surname>Froguel</surname>
                  </persName>
                  <email type="md5">e3a7bff8517ce0850f8fbc4a6b8ece30</email>
                  <email type="domain">good.ibl.fr</email>
                  <idno type="idhal" notation="numeric">1315149</idno>
                  <idno type="halauthorid" notation="string">154897-1315149</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-2972-0784</idno>
                  <affiliation ref="#struct-1238"/>
                  <affiliation ref="#struct-18570"/>
                  <affiliation ref="#struct-18946"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">7336</idno>
                <idno type="issn">1061-4036</idno>
                <idno type="eissn">1546-1718</idno>
                <title level="j">Nature Genetics</title>
                <imprint>
                  <publisher>Nature Publishing Group</publisher>
                  <biblScope unit="volume">37</biblScope>
                  <biblScope unit="issue">8</biblScope>
                  <biblScope unit="pp">863-7</biblScope>
                  <date type="datePub">2005-08</date>
                  <date type="dateEpub">2005-07-17</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1038/ng1604</idno>
              <idno type="prodinra">249385</idno>
              <idno type="pubmed">16025115</idno>
              <ref target="http://hal.archives-ouvertes.fr/hal-00174474" type="seeAlso"/>
              <ref target="http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&amp;term=16025115" type="seeAlso"/>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Child</term>
                <term xml:lang="en">Adult</term>
                <term xml:lang="en">Case-Control Studies</term>
                <term xml:lang="en">Diabetes Mellitus</term>
                <term xml:lang="en">Type 2</term>
                <term xml:lang="en">Genetic Predisposition to Disease</term>
                <term xml:lang="en">Glucose Tolerance Test</term>
                <term xml:lang="en">Haplotypes</term>
                <term xml:lang="en">Humans</term>
                <term xml:lang="en">Obesity</term>
                <term xml:lang="en">Phosphoric Diester Hydrolases</term>
                <term xml:lang="en">Pyrophosphatases</term>
                <term xml:lang="en">RNA</term>
                <term xml:lang="fr">Messenger</term>
              </keywords>
              <classCode scheme="mesh">Adult</classCode>
              <classCode scheme="mesh">Case-Control Studies</classCode>
              <classCode scheme="mesh">Haplotypes</classCode>
              <classCode scheme="mesh">Humans</classCode>
              <classCode scheme="mesh">Obesity</classCode>
              <classCode scheme="mesh">Phosphoric Diester Hydrolases</classCode>
              <classCode scheme="mesh">Pyrophosphatases</classCode>
              <classCode scheme="mesh">RNA, Messenger</classCode>
              <classCode scheme="mesh">Child</classCode>
              <classCode scheme="mesh">Diabetes Mellitus, Type 2</classCode>
              <classCode scheme="mesh">Genetic Predisposition to Disease</classCode>
              <classCode scheme="mesh">Glucose Tolerance Test</classCode>
              <classCode scheme="halDomain" n="sdv.gen.gh">Life Sciences [q-bio]/Genetics/Human genetics</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>We identified a locus on chromosome 6q16.3-q24.2 (ref. 1) associated with childhood obesity that includes 2.4 Mb common to eight genome scans for type 2 diabetes (T2D) or obesity. Analysis of the gene ENPP1 (also called PC-1), a candidate for insulin resistance, in 6,147 subjects showed association between a three-allele risk haplotype (K121Q, IVS20delT-11 and A--&gt;G+1044TGA; QdelTG) and childhood obesity (odds ratio (OR) = 1.69, P = 0.0006), morbid or moderate obesity in adults (OR = 1.50, P = 0.006 or OR = 1.37, P = 0.02, respectively) and T2D (OR = 1.56, P = 0.00002). The Genotype IBD Sharing Test suggested that this obesity-associated ENPP1 risk haplotype contributes to the observed chromosome 6q linkage with childhood obesity. The haplotype confers a higher risk of glucose intolerance and T2D to obese children and their parents and associates with increased serum levels of soluble ENPP1 protein in children. Expression of a long ENPP1 mRNA isoform, which includes the obesity-associated A--&gt;G+1044TGA SNP, was specific for pancreatic islet beta cells, adipocytes and liver. These findings suggest that several variants of ENPP1 have a primary role in mediating insulin resistance and in the development of both obesity and T2D, suggesting that an underlying molecular mechanism is common to both conditions.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-1238" status="VALID">
          <orgName>Génétique des maladies multifactorielles</orgName>
          <orgName type="acronym">GMM</orgName>
          <desc>
            <address>
              <addrLine>1 Rue du professeur Calmette - BP 245 59019 LILLE CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www-good.pasteur-lille.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-361611" type="direct"/>
            <relation name="UMR8090" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300166" status="VALID">
          <idno type="ROR">https://ror.org/05k9skc85</idno>
          <orgName>Institut Pasteur de Lille</orgName>
          <date type="start">1894</date>
          <desc>
            <address>
              <addrLine>1 Rue du Professeur Calmette - Lille Cedex - 59019</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.pasteur-lille.fr/accueil/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301247" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-306007" status="VALID">
          <idno type="IdRef">03412232X</idno>
          <orgName>Hôpital Hôtel-Dieu [Paris]</orgName>
          <desc>
            <address>
              <addrLine>1, place du Parvis Notre-Dame75004 Paris</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-93488" status="VALID">
          <idno type="IdRef">028035747</idno>
          <idno type="ISNI">0000000419368390</idno>
          <idno type="ROR">https://ror.org/04sjchr03</idno>
          <idno type="Wikidata">Q1067935</idno>
          <orgName>Université Laval [Québec]</orgName>
          <orgName type="acronym">ULaval</orgName>
          <desc>
            <address>
              <addrLine>2325, rue de l'Université Québec G1V 0A6</addrLine>
              <country key="CA"/>
            </address>
            <ref type="url">https://www.ulaval.ca/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-26889" status="VALID">
          <orgName>Centre national d'études et de formation pour l'enfance inadaptée</orgName>
          <orgName type="acronym">CNEFEI</orgName>
          <date type="end">2005-12-31</date>
          <desc>
            <address>
              <addrLine>58-60 Avenue des Landes92150 Suresnes</addrLine>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-235755" status="OLD">
          <orgName>Unité de Recherche en Epidémiologie Nutritionnelle</orgName>
          <orgName type="acronym">UREN</orgName>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>UFR Santé, Médecine et Biologie Humaine - 74 rue Marcel Cachin 93017 Bobigny Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-paris13.fr/uren/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-15786" type="direct"/>
            <relation name="UR1125" active="#struct-92114" type="direct"/>
            <relation active="#struct-300351" type="direct"/>
            <relation active="#struct-303171" type="direct"/>
            <relation name="U557" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-184952" status="VALID">
          <idno type="ROR">https://ror.org/0246mbd04</idno>
          <orgName>Centre Hospitalier Sud Francilien - Centre Hospitalier d'Evry</orgName>
          <orgName type="acronym">CHSF</orgName>
          <desc>
            <address>
              <addrLine>40 Avenue Serge Dassault - 91100 Corbeil-Essonnes</addrLine>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-530598" status="VALID">
          <orgName>Paracelsus Medizinische Privatuniversität = Paracelsus Medical University</orgName>
          <orgName type="acronym">PMU</orgName>
          <date type="start">2003-01-01</date>
          <desc>
            <address>
              <addrLine>Strubergasse 21, 5020 Salzburg</addrLine>
              <country key="AT"/>
            </address>
            <ref type="url">https://www.pmu.ac.at/en/home.html</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-2857" status="OLD">
          <orgName>Recherche en épidémiologie et biostatistique</orgName>
          <desc>
            <address>
              <addrLine>16, Avenue Paul Vaillant-Couturier 94807 VILLEJUIF CEDEX</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-92966" type="direct"/>
            <relation name="U780" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-531" status="VALID">
          <orgName>Systèmes Macromoléculaires et Physiopathologie Humaine</orgName>
          <orgName type="acronym">SMPH</orgName>
          <desc>
            <address>
              <addrLine>46, Allée d'Italie - BP 69007 69007 LYON</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300449" type="direct"/>
            <relation name="UMR2714" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-2807" status="OLD">
          <orgName>Epidémiologie cardiovasculaire et métabolique</orgName>
          <desc>
            <address>
              <addrLine>Hôpital Paul Brousse 16, Avenue Paul Vaillant-Couturier 94807 VILLEJUIF CEDEX</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-92966" type="direct"/>
            <relation name="U258" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-360410" status="VALID">
          <orgName>CHU Trousseau [APHP]</orgName>
          <desc>
            <address>
              <addrLine>26 Avenue du Dr Arnold Netter, 75012 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.aphp.fr/contenu/hopital-armand-trousseau-1</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
            <relation active="#struct-413221" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-18903" status="OLD">
          <orgName>Déterminants Biologiques et Comportementaux des Obésités</orgName>
          <desc>
            <address>
              <addrLine>Groupe d'expertise collective de l'Inserm</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.senat.fr/rap/r05-008/r05-00813.html</ref>
          </desc>
          <listRelation>
            <relation active="#struct-93591" type="direct"/>
            <relation active="#struct-300068" type="direct"/>
            <relation active="#struct-300142" type="direct"/>
            <relation active="#struct-306983" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-99711" status="VALID">
          <orgName>Service de nutrition</orgName>
          <desc>
            <address>
              <addrLine>PARIS</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
            <relation active="#struct-306775" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-11965" status="OLD">
          <orgName>Nutrition et obésité : approches génétique et transcriptomique</orgName>
          <desc>
            <address>
              <addrLine>Hotel Dieu 1 Place du Parvis de Notre Dame 75181 Paris Cedex 04</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-93591" type="direct"/>
            <relation active="#struct-300439" type="direct"/>
            <relation name="U755" active="#struct-303623" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-28185" status="VALID">
          <orgName>Département de nutrition</orgName>
          <desc>
            <address>
              <addrLine>HOTEL-DIEU Groupement hospitalier universitaire Ouest 1, place du Parvis Notre-Dame 75 PARIS 4ème</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.aphp.fr/index.php?module=portail&amp;action=afficherPortail&amp;vue=portail&amp;NIHOPITAL=20</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300068" type="direct"/>
            <relation active="#struct-300142" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-18944" status="VALID">
          <orgName>Service d'endocrinologie pédiatrique [CHU Lille]</orgName>
          <desc>
            <address>
              <addrLine>Lille</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300137" type="direct"/>
            <relation active="#struct-425779" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1142" status="OLD">
          <orgName>Liquides Ioniques et Interfaces Chargées</orgName>
          <orgName type="acronym">LI2C</orgName>
          <desc>
            <address>
              <addrLine>Bât. F-74 - Boîte 51 4 Place Jussieu 75252 PARIS CEDEX 05</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ccr.jussieu.fr/li2c/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-93591" type="direct"/>
            <relation active="#struct-301585" type="direct"/>
            <relation active="#struct-564132" type="indirect"/>
            <relation name="UMR7612" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-190541" status="VALID">
          <idno type="ROR">https://ror.org/043mz5j54</idno>
          <orgName>University of California [San Francisco]</orgName>
          <orgName type="acronym">UC San Francisco</orgName>
          <desc>
            <address>
              <addrLine>505 Parnassus Ave, San Francisco, CA 94143</addrLine>
              <country key="US"/>
            </address>
            <ref type="url">https://www.ucsf.edu/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-471291" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-69530" status="VALID">
          <idno type="ISNI">0000000121138111</idno>
          <idno type="ROR">https://ror.org/041kmwe10</idno>
          <orgName>Imperial College London</orgName>
          <date type="start">1907-01-01</date>
          <desc>
            <address>
              <addrLine>South Kensington Campus, London SW7 2AZ</addrLine>
              <country key="GB"/>
            </address>
            <ref type="url">http://www.imperial.ac.uk/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-18570" status="VALID">
          <orgName>Section of Genomic Medicine</orgName>
          <desc>
            <address>
              <addrLine>W2 0NN London</addrLine>
              <country key="GB"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-69530" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-18946" status="VALID">
          <orgName>Genome Centre</orgName>
          <desc>
            <address>
              <addrLine>John Vane Science Centre, Queen Mary, University of London, Charterhouse Square, London EC1M 6BQ, Tel: +44 (0)20 7882 2055, Fax: +44 (0)20 7882 8406</addrLine>
              <country key="GB"/>
            </address>
            <ref type="url">http://www.smd.qmul.ac.uk/gc/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-69530" type="direct"/>
            <relation active="#struct-306894" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-361611" status="OLD">
          <idno type="IdRef">026404389</idno>
          <idno type="ISNI">0000000120977060</idno>
          <orgName>Université de Lille, Droit et Santé</orgName>
          <date type="end">2017-12-31</date>
          <desc>
            <address>
              <addrLine>42 rue Paul Duez 59000 Lille</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-lille2.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-301247" status="VALID">
          <orgName>Pasteur Network (Réseau International des Instituts Pasteur)</orgName>
          <desc>
            <address>
              <addrLine>25, rue du Dr Roux 75724 Paris Cedex 15</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://pasteur-network.org/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300068" status="VALID">
          <idno type="ROR">https://ror.org/00pg5jh14</idno>
          <orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName>
          <orgName type="acronym">AP-HP</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-15786" status="VALID">
          <idno type="ROR">https://ror.org/05f82e368</idno>
          <orgName>Université Paris 13</orgName>
          <orgName type="acronym">UP13</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-paris13.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-92114" status="OLD">
          <idno type="ROR">https://ror.org/01x3gbx83</idno>
          <orgName>Institut National de la Recherche Agronomique</orgName>
          <orgName type="acronym">INRA</orgName>
          <date type="start">1946-05-18</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inra.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300351" status="VALID">
          <idno type="IdRef">027404978</idno>
          <idno type="ISNI">0000000121690459</idno>
          <idno type="ROR">https://ror.org/0175hh227</idno>
          <orgName>Conservatoire National des Arts et Métiers [Cnam]</orgName>
          <orgName type="acronym">Cnam</orgName>
          <desc>
            <address>
              <addrLine>292 Rue Saint-Martin, 75003 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cnam.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-303171" status="VALID">
          <idno type="IdRef">19077990X</idno>
          <idno type="ROR">https://ror.org/001z21q04</idno>
          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-92966" status="OLD">
          <idno type="ROR">https://ror.org/028rypz17</idno>
          <orgName>Université Paris-Sud - Paris 11</orgName>
          <orgName type="acronym">UP11</orgName>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>Bâtiment 300 - 91405 Orsay cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.u-psud.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300449" status="VALID">
          <idno type="ISNI">0000 0004 0387 6489</idno>
          <idno type="ROR">https://ror.org/03hf69k85</idno>
          <idno type="Wikidata">Q2904021</idno>
          <orgName>BIOMERIEUX [Lyon, France]</orgName>
          <desc>
            <address>
              <addrLine>376, chemin de l'Orme. 69280 Marcy l'Etoile.</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.biomerieux.com/en/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-413221" status="VALID">
          <idno type="IdRef">221333754</idno>
          <idno type="ROR">https://ror.org/02en5vm52</idno>
          <orgName>Sorbonne Université</orgName>
          <orgName type="acronym">SU</orgName>
          <date type="start">2018-01-01</date>
          <desc>
            <address>
              <addrLine>21 rue de l’École de médecine - 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.sorbonne-universite.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-93591" status="OLD">
          <idno type="ROR">https://ror.org/02en5vm52</idno>
          <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
          <orgName type="acronym">UPMC</orgName>
          <date type="end">2017-12-31</date>
          <desc>
            <address>
              <addrLine>4 place Jussieu - 75005 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.upmc.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300142" status="VALID">
          <orgName>Hôtel-Dieu</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-306983" status="INCOMING">
          <orgName>EA3502</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-306775" status="INCOMING">
          <orgName>Hôpital de l'Hôtel-Dieu</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300439" status="VALID">
          <orgName>IFR58</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300137" status="VALID">
          <idno type="ISNI">0000 0004 0593 6676</idno>
          <idno type="ROR">https://ror.org/01e8kn913</idno>
          <orgName>Hôpital Jeanne de Flandre [Lille]</orgName>
          <desc>
            <address>
              <addrLine>Avenue Eugène Avinée, 59000 Lille</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-lille.fr/hopital-jeanne-de-flandre/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-425779" status="VALID">
          <idno type="IdRef">034424636</idno>
          <idno type="ISNI">0000000404718845</idno>
          <idno type="ROR">https://ror.org/02ppyfa04</idno>
          <idno type="Wikidata">Q2945741</idno>
          <orgName>Centre Hospitalier Régional Universitaire [CHU Lille]</orgName>
          <orgName type="acronym">CHRU Lille</orgName>
          <desc>
            <address>
              <addrLine>CHU/CHRU Lille - 2, avenue Oscar Lambret - 59037 Lille Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chru-lille.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301585" status="VALID">
          <idno type="IdRef">028114779</idno>
          <idno type="ISNI">000000009591493X</idno>
          <idno type="ROR">https://ror.org/03zx86w41</idno>
          <orgName>Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris</orgName>
          <orgName type="acronym">ESPCI Paris</orgName>
          <date type="start">1882-10-01</date>
          <desc>
            <address>
              <addrLine>10 rue Vauquelin, 75231 Paris cedex 05</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.espci.psl.eu/fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-564132" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-564132" status="VALID">
          <idno type="IdRef">241597595</idno>
          <idno type="ISNI">0000 0004 1784 3645</idno>
          <idno type="ROR">https://ror.org/013cjyk83</idno>
          <orgName>Université Paris Sciences et Lettres</orgName>
          <orgName type="acronym">PSL</orgName>
          <desc>
            <address>
              <addrLine>60 rue Mazarine 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.psl.eu/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-471291" status="VALID">
          <idno type="ROR">https://ror.org/00pjdza24</idno>
          <orgName>University of California</orgName>
          <orgName type="acronym">UC</orgName>
          <date type="start">1869-01-01</date>
          <desc>
            <address>
              <country key="US"/>
            </address>
            <ref type="url">https://www.universityofcalifornia.edu/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-306894" status="INCOMING">
          <orgName>Hammersmith campus</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>