The hematopoietic niche: a Drosophila model, at last. - Archive ouverte HAL
Article Dans Une Revue Cell Cycle Année : 2007

The hematopoietic niche: a Drosophila model, at last.

Résumé

The niche provides a specialised microenvironment necessary for maintenance of stem cells in a non differentiated state. While the hematopoietic stem cell (HSC) niche in vertebrates was the first to be recognized, Drosophila niches supporting germline stem cells were characterised first. Recent evidence for the existence of a niche maintaining hematopoietic precursors in Drosophila opens the way to study in vivo the niche/hematopoietic precursors interactions. The availability of a large collection of cell markers, mutants and sophisticated genetic tools makes Drosophila an attractive model for investigating the cellular and molecular mechanisms that are involved in these interactions.

Dates et versions

hal-00169739 , version 1 (04-09-2007)

Identifiants

Citer

Michèle Crozatier, Joanna Krzemien, Alain Vincent. The hematopoietic niche: a Drosophila model, at last.. Cell Cycle, 2007, 6 (12), pp.1443-4. ⟨10.4161/cc.6.12.4370⟩. ⟨hal-00169739⟩
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