An Efficient, Stereoselective Approach to syn-1,2-Diols Protected as Cyclic Carbonates - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Organic Chemistry Année : 2004

An Efficient, Stereoselective Approach to syn-1,2-Diols Protected as Cyclic Carbonates

Yves Allenbach
Xavier Ariza
  • Fonction : Auteur correspondant
  • PersonId : 841759

Connectez-vous pour contacter l'auteur

Résumé

Enantioenriched 4-hydroxyalk-2-ynyl carbonates (or benzoates) have been prepared by stereoselective zinc-mediated addition of alkyl 2-propynyl carbonates (or their benzoate analogues) to aldehydes. Their partial reduction to Z-olefins followed by cyclization under mild Pd-catalyzed conditions allowed a straightforward access to enantioenriched syn-1,2-diols protected as cyclic carbonates.

Domaines

Chimie organique

Dates et versions

hal-00165650 , version 1 (26-07-2007)

Identifiants

Citer

Yohan Georges, Yves Allenbach, Xavier Ariza, Jean-Marc Campagne, Jordi Garcia. An Efficient, Stereoselective Approach to syn-1,2-Diols Protected as Cyclic Carbonates. Journal of Organic Chemistry, 2004, 69, pp.7387. ⟨10.1021/jo048985g⟩. ⟨hal-00165650⟩
28 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More