Microwave-Assisted Copper-Catalyzed Sonogashira Reaction in PEG solvent
Résumé
A catalytic system composed of copper salt, potassium carbonate and appropriate poly(ethylene glycol) (PEG ; liquid or solid, various molecular weight : 300< MW<3400 was developed to perform a Sonogashira arylation under microwave activation. In the presence of copper(I) iodide, various substituted diphenyl-acetylenes could be synthesized.