Exons, introns and DNA thermodynamics - Archive ouverte HAL Access content directly
Journal Articles Physical Review Letters Year : 2005

Exons, introns and DNA thermodynamics


The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis. We have analyzed the melting behavior of randomly selected human cDNA sequences obtained from the genomic DNA by removing all introns. A clear correspondence is observed between exons and melting domains. This finding may provide new insights in the physical mechanisms underlying the evolution of genes.
Fichier principal
Vignette du fichier
0409034.pdf (177.54 Ko) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

hal-00128506 , version 1 (11-07-2022)



Enrico Carlon, Mehdi Lejard Malki, Ralf Blossey. Exons, introns and DNA thermodynamics. Physical Review Letters, 2005, 94, pp.178101. ⟨10.1103/PhysRevLett.94.178101⟩. ⟨hal-00128506⟩
14 View
15 Download



Gmail Facebook X LinkedIn More