MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula. - Archive ouverte HAL
Article Dans Une Revue Genes and Development Année : 2006

MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula.

Résumé

In the model legume Medicago truncatula, we identified a new transcription factor of the CCAAT-binding family, MtHAP2-1, for which RNA interference (RNAi) and in situ hybridization experiments indicate a key role during nodule development, possibly by controlling nodule meristem function. We could also show that MtHAP2-1 is regulated by microRNA169, whose overexpression leads to the same nodule developmental block as MtHAP2-1 RNAi constructs. The complementary expression pattern of miR169 and MtHAP2-1 and the phenotype of miR169-resistant MtHAP2-1 nodules strongly suggest, in addition, that the miR169-mediated restriction of MtHAP2-1 expression to the nodule meristematic zone is essential for the differentiation of nodule cells.

Dates et versions

hal-00121505 , version 1 (20-12-2006)

Identifiants

Citer

Jean-Philippe Combier, Florian Frugier, Françoise de Billy, Adnane Boualem, Fikri El-Yahyaoui, et al.. MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula.. Genes and Development, 2006, 20 (22), pp.3084-8. ⟨10.1101/gad.402806⟩. ⟨hal-00121505⟩
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