Bio-specific recognition and applications: from molecular to colloidal scales - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Physics: Condensed Matter Année : 2004

Bio-specific recognition and applications: from molecular to colloidal scales

Résumé

Biomolecules have the well-known ability to build reversible complexes. Indeed, antigens and antibodies or adhesion molecules are able to recognize one another with a strong affinity and a very high specificity. This paper first reviews the various techniques and related results about binding and unbinding, at the scale of a unique ligand/receptor couple. One important biotechnological application arising from these recognition phenomena concerns immuno-diagnosis, which is essentially based on the formation of these specific complexes. We show how the physics of colloids associated with the growing scientific background concerning molecular recognition helps in rationalizing and inventing new diagnostic strategies. Finally the concept of colloidal self-assembling systems as biosensors is presented as directly impacting the most important questions related to molecular recognition and their biotechnological implications.
Fichier non déposé

Dates et versions

hal-00105278 , version 1 (10-10-2006)

Identifiants

Citer

Jean Baudry, Emanuel Bertrand, Nicolas Lequeux, Jérôme Bibette. Bio-specific recognition and applications: from molecular to colloidal scales. Journal of Physics: Condensed Matter, 2004, 16, pp.R469. ⟨10.1088/0953-8984/16/15/R02⟩. ⟨hal-00105278⟩
65 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More