Objectives : This paper presents a new simulator for maxillo-facial surgery, that gathers the dental and the maxillo-facial analyses together into a single computer-assisted procedure. The idea is first to propose a repositioning of the maxilla, via the introduction of a 3D cephalometry, applied to a 3D virtual model of the patient's skull. Then, orthodontic data are integrated into this model, thanks to optical measurements of teeth plaster casts. Materials and Methods : The feasibility of the maxillo-facial demonstrator was first evaluated on a dry skull. To simulate malformations (and thus to simulate a "real" patient), the skull was modified and manually cut by the surgeon, in order to generate a given maxillo-facial malformation (with asymmetries in the sagittal, frontal and axial planes). Results : The validation of our simulator consisted in evaluating its ability to propose a bone repositioning diagnosis that will put the skull as it was in its original configuration. A first qualitative validation is provided in this paper, with a 1.5-mm error in the repositioning diagnosis. Conclusions : These results mainly validate the concept of a maxillo-facial numerical simulator that integrates 3D cephalometry and guarantees a correct dental occlusion.