A Kernel for Protein Secondary Structure Prediction
Résumé
Multi-class support vector machines have already proved efficient in protein secondary structure prediction as ensemble methods, to combine the outputs of sets of classifiers based on different principles. In this chapter, their implementation as basic prediction methods, processing the primary structure or the profile of multiple alignments, is investigated. A kernel devoted to the task is introduced, which incorporates high-level pieces of knowledge. Initial experimental results illustrate the potential of this approach.