Abstract Over the past few decades, intelligent transportation systems (ITS) have emerged as an effective way to improve the performance of transportation systems. ITS provide innovative services, enhance travel safety, provide travellers with more choices, and make transportation systems more efficient. Multi-agent systems (MAS), which define autonomous interacting entities, are suitable for modelling distributed and intelligent systems in general and ITS in particular. This paper provides an in-depth review of multi-agent systems applied to Advanced Public Transportation Systems (APTS), a subclass of ITS dedicated to managing public transportation networks. We carefully analysed 38 papers in this study, published in 19 journals during 31 years (1990–2020). We perform a synthetic analysis of the trends in this domain and a qualitative analysis focused on multi-agent systems’ dimensions and properties. We show that the MAS approach is well suited to the real-time management of disturbances thanks to their delegation process, and their pro-activeness and autonomy properties.